| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 3 | 2 | 0 | 0 | 1 | 0 | – | 1 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 1 | – | 0 | 4 | 5 | 1 | 2 | 3 | 13 |
| Bud | 10 | 1 | 7 | 9 | 0 | 5 | – | 6 | 4 | 5 | 8 | 10 | 1 | 0 | 0 | 2 | – | 2 | 2 | 1 | 0 | 1 | 0 | 3 |
| Bud Neck | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 1 | 2 | 2 |
| Bud Site | 1 | 0 | 3 | 1 | 0 | 2 | – | 1 | 4 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | – | 0 | – | – | – | – | – | – |
| Cell Periphery | 3 | 6 | 3 | 4 | 2 | 3 | – | 1 | 0 | 4 | 1 | 1 | 3 | 8 | 8 | 1 | – | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cytoplasm | 16 | 1 | 4 | 6 | 3 | 6 | – | 6 | 3 | 2 | 3 | 2 | 0 | 4 | 8 | 4 | – | 2 | 11 | 0 | 0 | 0 | 0 | 0 |
| Endoplasmic Reticulum | 3 | 2 | 2 | 3 | 3 | 2 | – | 2 | 3 | 3 | 3 | 2 | 0 | 1 | 1 | 0 | – | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Endosome | 7 | 1 | 1 | 0 | 13 | 5 | – | 5 | 1 | 0 | 0 | 1 | 8 | 14 | 13 | 0 | – | 0 | 27 | 2 | 10 | 3 | 3 | 9 |
| Golgi | 2 | 19 | 0 | 2 | 1 | 1 | – | 0 | 1 | 0 | 0 | 0 | 15 | 27 | 31 | 6 | – | 7 | 18 | 18 | 6 | 7 | 10 | 17 |
| Mitochondria | 318 | 193 | 202 | 244 | 206 | 274 | – | 323 | 327 | 258 | 300 | 298 | 186 | 256 | 216 | 3 | – | 1 | 268 | 205 | 159 | 111 | 127 | 153 |
| Nucleus | 4 | 0 | 0 | 1 | 0 | 1 | – | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | – | 0 | 2 | 0 | 0 | 1 | 0 | 0 |
| Nuclear Periphery | 17 | 11 | 10 | 15 | 23 | 43 | – | 36 | 49 | 38 | 32 | 43 | 22 | 17 | 16 | 0 | – | 2 | 2 | 1 | 1 | 2 | 2 | 2 |
| Nucleolus | 21 | 6 | 23 | 19 | 29 | 52 | – | 53 | 49 | 39 | 36 | 38 | 13 | 7 | 15 | 0 | – | 0 | 2 | 2 | 2 | 3 | 3 | 4 |
| Peroxisomes | 8 | 8 | 5 | 9 | 13 | 4 | – | 5 | 3 | 3 | 3 | 4 | 14 | 14 | 9 | 0 | – | 1 | 13 | 4 | 22 | 7 | 10 | 16 |
| SpindlePole | 2 | 1 | 1 | 1 | 2 | 0 | – | 4 | 4 | 4 | 1 | 0 | 2 | 4 | 2 | 0 | – | 0 | 3 | 0 | 1 | 0 | 1 | 1 |
| Vac/Vac Membrane | 59 | 37 | 8 | 5 | 15 | 10 | – | 15 | 7 | 5 | 7 | 8 | 24 | 24 | 31 | 2 | – | 1 | 19 | 8 | 1 | 4 | 7 | 8 |
| Unique Cell Count | 372 | 220 | 210 | 258 | 244 | 317 | 377 | 344 | 284 | 322 | 317 | 215 | 297 | 266 | 16 | 17 | 380 | 254 | 214 | 149 | 175 | 236 | ||
| Labelled Cell Count | 474 | 288 | 269 | 319 | 311 | 408 | 461 | 455 | 366 | 396 | 409 | 290 | 379 | 351 | 19 | 18 | 380 | 254 | 214 | 149 | 175 | 236 | ||
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 7.9 | 13.0 | 7.2 | 8.7 | 8.7 | 8.0 | – | 8.5 | 7.8 | 7.9 | 8.0 | 7.8 | 10.3 | 10.8 | 10.1 | 9.6 | – | 10.5 | 11.6 | 12.8 | 12.6 |
| Std Deviation (1e-4) | 2.0 | 2.6 | 1.9 | 2.9 | 2.2 | 2.2 | – | 2.8 | 2.7 | 2.7 | 2.5 | 2.6 | 2.1 | 2.3 | 2.3 | 2.3 | – | 2.8 | 2.9 | 3.2 | 3.1 |
| Intensity Change (Log2) | – | – | – | 0.27 | 0.28 | 0.15 | – | 0.24 | 0.13 | 0.14 | 0.16 | 0.13 | 0.52 | 0.59 | 0.49 | 0.43 | – | 0.55 | 0.69 | 0.83 | 0.81 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cortical Patches | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Bud | 0.1 | 0 | 0 | – | 0 | 0 | -1.1 | -0.6 | -0.1 | 0 | 0 | 0 | 0 | – | 0 |
| Bud Neck | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Bud Site | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Cell Periphery | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Cytoplasm | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.8 | 0 | – | 0 |
| Endoplasmic Reticulum | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Endosome | 0 | 3.0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 2.8 | 2.8 | 0 | – | 0 |
| Golgi | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 3.9 | 4.5 | 5.1 | 0 | – | 0 |
| Mitochondria | -0.8 | -4.1 | -3.7 | – | -4.0 | -0.6 | -2.3 | -1.5 | -1.1 | -3.5 | -3.8 | -5.0 | -10.3 | – | -11.6 |
| Nucleus | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Nuclear Periphery | 0.5 | 1.9 | 3.3 | – | 2.1 | 3.5 | 3.2 | 2.2 | 3.3 | 2.1 | 0.5 | 0.6 | 0 | – | 0 |
| Nucleolus | -1.4 | 0.3 | 1.8 | – | 1.1 | 1.1 | 0.9 | 0.1 | 0.4 | -1.8 | -4.0 | -2.1 | 0 | – | 0 |
| Peroxisomes | 0.7 | 1.6 | 0 | – | 0 | 0 | 0 | 0 | 0 | 2.1 | 1.4 | 0.6 | 0 | – | 0 |
| SpindlePole | 0 | 0 | 0 | – | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | – | 0 |
| Vacuole | -1.2 | 1.1 | -0.4 | – | 0.1 | -1.2 | -1.4 | -1.1 | -0.8 | 2.9 | 1.9 | 3.1 | 0 | – | 0 |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasmic Foci | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Eisosomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Lipid Particles | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| None | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Punctate Nuclear | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 33.2586 | 31.4801 | 20.7641 | 41.3046 | 35.5116 | 43.0168 | 49.5125 | 38.1916 | 41.7403 | 44.3089 |
| Translational Efficiency | 2.0642 | 1.8567 | 2.9266 | 1.0534 | 1.8543 | 2.4728 | 1.6742 | 2.5411 | 2.3624 | 2.2463 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | – |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 330 | 958 | 141 | 246 | 1483 | 1451 | 17 | 393 | 1813 | 2409 | 158 | 639 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 908.81 | 980.91 | 1219.65 | 1069.28 | 894.30 | 940.97 | 1255.54 | 1047.27 | 896.94 | 956.85 | 1223.51 | 1055.74 |
| Standard Deviation | 139.33 | 179.30 | 213.81 | 161.83 | 154.86 | 164.94 | 286.75 | 175.55 | 152.26 | 171.91 | 223.09 | 170.73 |
| Intensity Change Log 2 | — | 0.110142 | 0.424417 | 0.234589 | — | 0.073390 | 0.489477 | 0.227803 | — | 0.092031 | 0.457052 | 0.231227 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.001304 | 0.006144 | 0.004020 | 0.005067 | 0.001520 | 0.004439 | 0.091869 | 0.002107 | 0.001481 | 0.005117 | 0.013472 | 0.003246 |
| Bud Neck | 0.002143 | 0.001465 | 0.014975 | 0.016468 | 0.000993 | 0.001306 | 0.009695 | 0.009688 | 0.001203 | 0.001369 | 0.014407 | 0.012299 |
| Bud Site | 0.002838 | 0.004952 | 0.011919 | 0.013745 | 0.001757 | 0.003439 | 0.083022 | 0.016763 | 0.001954 | 0.004040 | 0.019570 | 0.015601 |
| Cell Periphery | 0.000207 | 0.000277 | 0.000276 | 0.000369 | 0.000279 | 0.000320 | 0.001546 | 0.000199 | 0.000266 | 0.000303 | 0.000413 | 0.000264 |
| Cytoplasm | 0.000273 | 0.000646 | 0.001265 | 0.001359 | 0.000283 | 0.001408 | 0.061702 | 0.001812 | 0.000281 | 0.001105 | 0.007768 | 0.001638 |
| Cytoplasmic Foci | 0.019055 | 0.028514 | 0.090522 | 0.060045 | 0.009104 | 0.029773 | 0.054086 | 0.056081 | 0.010915 | 0.029272 | 0.086602 | 0.057607 |
| Eisosomes | 0.000072 | 0.000127 | 0.000134 | 0.000143 | 0.000087 | 0.000097 | 0.000617 | 0.000124 | 0.000084 | 0.000109 | 0.000186 | 0.000132 |
| Endoplasmic Reticulum | 0.000465 | 0.000353 | 0.001543 | 0.000821 | 0.000287 | 0.000371 | 0.013887 | 0.000444 | 0.000319 | 0.000364 | 0.002871 | 0.000589 |
| Endosome | 0.024263 | 0.031465 | 0.064115 | 0.075990 | 0.012572 | 0.041947 | 0.088590 | 0.052266 | 0.014700 | 0.037779 | 0.066748 | 0.061399 |
| Golgi | 0.018919 | 0.044915 | 0.056772 | 0.030139 | 0.013205 | 0.045785 | 0.049398 | 0.040059 | 0.014245 | 0.045439 | 0.055979 | 0.036240 |
| Lipid Particles | 0.009944 | 0.011586 | 0.024329 | 0.010192 | 0.008240 | 0.007418 | 0.019582 | 0.007901 | 0.008550 | 0.009075 | 0.023818 | 0.008783 |
| Mitochondria | 0.877977* | 0.816430* | 0.547004* | 0.608209* | 0.926239* | 0.819717* | 0.323283* | 0.661901* | 0.917455* | 0.818410* | 0.522933* | 0.641231* |
| Mitotic Spindle | 0.006279 | 0.003368 | 0.086866 | 0.054892 | 0.000756 | 0.003661 | 0.058211 | 0.032695 | 0.001762 | 0.003545 | 0.083783 | 0.041241 |
| None | 0.000524 | 0.000456 | 0.000649 | 0.000481 | 0.000451 | 0.000351 | 0.001489 | 0.000438 | 0.000464 | 0.000393 | 0.000739 | 0.000455 |
| Nuclear Periphery | 0.001693 | 0.000221 | 0.004319 | 0.003635 | 0.000315 | 0.000184 | 0.000638 | 0.000811 | 0.000566 | 0.000199 | 0.003923 | 0.001898 |
| Nuclear Periphery Foci | 0.002486 | 0.000366 | 0.007201 | 0.004127 | 0.000416 | 0.000309 | 0.002804 | 0.001346 | 0.000793 | 0.000332 | 0.006728 | 0.002417 |
| Nucleolus | 0.001227 | 0.000343 | 0.002482 | 0.003693 | 0.000612 | 0.000273 | 0.000321 | 0.002090 | 0.000724 | 0.000301 | 0.002250 | 0.002707 |
| Nucleus | 0.000517 | 0.000564 | 0.002213 | 0.002721 | 0.000556 | 0.000241 | 0.000238 | 0.000993 | 0.000549 | 0.000369 | 0.002001 | 0.001658 |
| Peroxisomes | 0.014909 | 0.036512 | 0.034441 | 0.073344 | 0.012886 | 0.021911 | 0.018837 | 0.085243 | 0.013254 | 0.027718 | 0.032762 | 0.080662 |
| Vacuole | 0.007714 | 0.005377 | 0.025975 | 0.023089 | 0.004263 | 0.008721 | 0.067621 | 0.015740 | 0.004891 | 0.007391 | 0.030456 | 0.018569 |
| Vacuole Periphery | 0.007192 | 0.005918 | 0.018980 | 0.011472 | 0.005179 | 0.008331 | 0.052565 | 0.011298 | 0.005545 | 0.007372 | 0.022593 | 0.011365 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | -3.51 | -2.18 | -2.29 | 0.55 | -0.55 | -3.47 | -1.93 | -0.86 | 2.75 | 1.91 | -4.76 | -2.19 | -2.26 | 2.02 | 1.86 |
| Bud Neck | 0.97 | -3.50 | -5.15 | -5.48 | -0.33 | -0.98 | -1.74 | -6.99 | -6.65 | -0.03 | -0.62 | -4.02 | -8.48 | -8.33 | 0.58 |
| Bud Site | -0.88 | -2.43 | -2.68 | -2.30 | -0.38 | -1.98 | -1.81 | -4.20 | -3.71 | 1.46 | -2.36 | -3.05 | -5.18 | -4.35 | 0.60 |
| Cell Periphery | -0.77 | -0.95 | -1.39 | -0.78 | -0.87 | -0.49 | -2.70 | 1.30 | 1.79 | 2.88 | -0.56 | -1.80 | 0.00 | 0.62 | 1.89 |
| Cytoplasm | -3.73 | -2.54 | -4.58 | -2.98 | -0.15 | -2.79 | -1.20 | -4.05 | -1.05 | 1.16 | -3.30 | -1.35 | -5.26 | -1.79 | 1.07 |
| Cytoplasmic Foci | -2.40 | -5.94 | -5.28 | -4.24 | 2.23 | -9.71 | -2.67 | -8.77 | -4.66 | -0.12 | -10.43 | -7.12 | -10.71 | -6.31 | 2.59 |
| Eisosomes | -4.30 | -3.44 | -4.18 | -0.95 | -0.41 | -0.86 | -1.95 | -2.17 | -1.77 | 1.81 | -2.54 | -2.93 | -3.58 | -1.97 | 1.51 |
| Endoplasmic Reticulum | 0.56 | -2.53 | -1.61 | -3.27 | 1.79 | -0.98 | -1.29 | -1.84 | -1.02 | 1.27 | -0.58 | -2.13 | -3.11 | -3.09 | 1.90 |
| Endosome | -1.50 | -4.56 | -5.85 | -5.34 | -1.09 | -10.05 | -1.79 | -8.08 | -1.95 | 0.84 | -10.03 | -6.23 | -10.57 | -5.11 | 0.54 |
| Golgi | -4.94 | -4.49 | -2.07 | 2.84 | 3.16 | -10.67 | -2.45 | -6.08 | 1.16 | 0.62 | -12.24 | -5.98 | -6.75 | 2.52 | 2.64 |
| Lipid Particles | -0.47 | -2.26 | -0.06 | 0.57 | 2.42 | 0.48 | -1.00 | 0.17 | -0.30 | 1.03 | -0.37 | -2.93 | -0.15 | 0.23 | 2.90 |
| Mitochondria | 3.69 | 9.84 | 9.71 | 8.00 | -1.57 | 11.84 | 5.96 | 13.15 | 7.56 | -3.27 | 13.07 | 13.01 | 17.34 | 10.86 | -3.50 |
| Mitotic Spindle | 1.02 | -5.56 | -5.51 | -6.12 | 1.93 | -4.70 | -1.09 | -6.54 | -5.90 | 0.47 | -2.57 | -5.91 | -8.87 | -8.47 | 2.89 |
| None | 0.75 | -1.52 | 0.66 | -0.33 | 2.46 | 0.94 | -2.29 | -0.04 | -0.92 | 2.28 | 0.98 | -3.47 | 0.01 | -0.96 | 3.43 |
| Nuclear Periphery | 1.53 | -1.69 | -1.10 | -2.31 | 0.36 | 1.28 | -1.14 | -2.73 | -3.97 | -0.57 | 1.90 | -3.03 | -2.19 | -2.94 | 1.64 |
| Nuclear Periphery Foci | 1.77 | -1.77 | -1.00 | -3.31 | 1.16 | 1.02 | -1.74 | -3.69 | -4.22 | 0.96 | 1.96 | -2.77 | -3.24 | -4.57 | 1.94 |
| Nucleolus | 1.48 | -0.96 | -1.73 | -2.51 | -0.68 | 1.12 | 0.99 | -1.89 | -2.38 | -2.33 | 1.58 | -1.41 | -2.76 | -3.46 | -0.41 |
| Nucleus | -0.10 | -1.39 | -1.86 | -1.72 | -0.30 | 0.82 | 0.90 | -0.86 | -1.60 | -1.66 | 0.49 | -1.30 | -1.89 | -2.30 | 0.24 |
| Peroxisomes | -4.12 | -3.16 | -5.61 | -3.47 | -3.41 | -3.41 | -0.64 | -8.17 | -7.04 | -5.27 | -5.76 | -3.89 | -10.03 | -7.69 | -5.76 |
| Vacuole | 1.29 | -3.60 | -4.41 | -5.59 | 0.50 | -3.67 | -1.67 | -5.43 | -3.07 | 1.36 | -2.77 | -4.29 | -7.55 | -5.98 | 1.90 |
| Vacuole Periphery | 0.73 | -3.02 | -2.10 | -3.70 | 1.98 | -3.12 | -1.33 | -2.66 | -1.26 | 1.16 | -2.23 | -3.41 | -3.71 | -2.57 | 2.17 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress |
| Localization | |
| Cell Percentages | mitochondrion (98%) |
| Cell Cycle Regulation | No |
| Subcompartmental Group | mito-2 |
Rtc6
Rtc6
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Rtc6-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
