Standard name
Human Ortholog
Description Delta adaptin-like subunit of the clathrin associated protein complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; suppressor of loss of casein kinase 1 function; the clathrin associated protein complex is also known as AP-3
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.12 0.2 0 0 0 0 0 0.05 0.05 0 0 0 0.19 0.21 0.16 0.11 0.08 0.12 0.05 0.05 0.09 0.05 0.05 0.06
Bud 0 0 0 0 0 0 0.06 0.06 0.1 0.05 0.1 0.11 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.05 0.14 0.11 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.1 0 0 0 0 0 0 0 0 0 0 0.16 0.13 0.12 0.05 0 0 0 0 0 0 0 0
Endosome 0.18 0 0.18 0.15 0.16 0.11 0.16 0.18 0.08 0.05 0 0.11 0.14 0.14 0.13 0.27 0.32 0.25 0.17 0.19 0.13 0.14 0.12 0.1
Golgi 0.62 0.27 0.49 0.31 0.33 0.08 0.08 0.06 0.06 0 0 0 0.54 0.57 0.64 0.35 0.38 0.54 0.73 0.56 0.69 0.7 0.73 0.76
Mitochondria 0.41 0.82 0.56 0.72 0.64 0.8 0.73 0.69 0.83 0.88 0.88 0.73 0.19 0.19 0.07 0.11 0.08 0.1 0 0.1 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0.06 0.05 0 0.08 0.08 0.08 0.06 0 0.11 0 0 0 0 0 0 0 0 0.06 0.05 0 0.05
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.09 0.05 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0 0 0 0 0 0 0 0 0 0 0 0.1 0.1 0.11 0.06 0.09 0.09 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 43 31 9 10 13 14 15 40 30 14 21 27 38 43 38 22 47 42 19 8 32 15 28 33
Bud 11 6 13 11 15 11 45 50 59 35 54 74 4 4 3 9 18 12 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 1 3 6 7 8 6 0 0 0 0 1 0 – – – – – –
Cell Periphery 0 1 0 1 2 1 4 3 8 1 4 4 4 4 1 1 2 1 0 0 0 0 0 0
Cytoplasm 3 5 7 10 11 8 10 13 6 10 11 8 13 13 11 30 62 26 0 1 0 0 0 2
Endoplasmic Reticulum 10 16 9 3 7 22 20 16 15 11 10 14 32 26 28 11 12 13 0 0 0 1 3 2
Endosome 64 0 62 39 69 56 120 151 44 37 22 76 28 28 31 56 183 87 67 34 47 43 66 60
Golgi 224 42 168 81 142 39 55 53 35 15 21 26 108 116 150 74 215 186 296 99 253 221 398 454
Mitochondria 149 130 194 187 279 397 534 590 474 632 456 510 39 39 17 23 46 34 6 16 7 13 16 13
Nucleus 0 2 0 0 2 1 0 3 0 0 1 0 0 0 0 0 3 2 0 1 0 0 0 0
Nuclear Periphery 0 0 5 1 1 3 5 8 3 9 3 3 2 3 0 1 1 1 0 0 0 0 1 0
Nucleolus 3 0 4 3 7 6 32 49 14 26 11 14 2 2 3 0 11 5 0 0 0 0 0 0
Peroxisomes 3 0 9 15 22 17 57 65 43 42 22 79 2 3 0 1 24 6 12 4 22 17 23 27
SpindlePole 4 0 3 1 7 5 16 28 23 21 14 30 6 6 7 15 50 16 0 1 0 1 1 0
Vac/Vac Membrane 24 7 5 3 10 12 13 11 3 5 3 15 20 20 27 13 52 30 2 7 1 0 1 2
Unique Cell Count 361 158 344 259 435 497 733 854 570 717 520 694 201 203 236 209 566 345 407 178 368 316 545 601
Labelled Cell Count 538 240 488 365 587 593 927 1083 763 865 661 886 298 307 316 256 727 461 407 178 368 316 545 601


Early Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.4 8.1 10.7 10.0 9.6 8.4 8.1 8.1 7.8 7.0 7.5 7.5 9.9 9.9 10.9 8.1 9.2 11.0 11.8 12.1 12.5
Std Deviation (1e-4) 1.4 1.4 1.8 1.5 1.6 1.5 1.5 1.7 1.7 1.5 1.7 1.6 1.4 1.4 1.2 1.4 1.7 2.1 1.5 1.7 1.8
Intensity Change (Log2) – – – -0.09 -0.15 -0.34 -0.39 -0.4 -0.45 -0.61 -0.52 -0.5 -0.1 -0.1 0.03 -0.4 -0.22 0.05 0.15 0.18 0.24

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.9 0.3 0.2 -0.6 1.6 1.9 -0.7 1.1 1.1 6.5 7.2 5.8 3.9 3.5 4.8
Bud 0.3 -0.2 -1.3 1.6 1.5 3.6 0.8 3.6 3.8 -1.2 -1.2 -1.8 0.3 -0.5 -0.2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.3 0.5 -0.5 -0.8 -0.6 0 -0.8 0.1 0 2.7 2.6 1.8 5.6 4.9 3.4
Endoplasmic Reticulum -1.3 -1.0 1.4 0.1 -0.8 0 -1.2 -0.7 -0.6 5.7 4.7 4.5 1.6 -0.5 0.9
Endosome -1.0 -0.8 -2.8 -0.7 -0.1 -4.7 -6.7 -6.7 -3.2 -1.2 -1.3 -1.6 2.4 4.7 2.3
Golgi -4.3 -4.6 -13.6 -15.6 -17.2 -15.0 -18.9 -15.6 -17.5 1.1 1.9 3.5 -3.1 -3.2 1.3
Mitochondria 4.0 2.2 7.3 5.4 4.2 8.8 11.7 10.4 5.5 -8.4 -8.5 -12.1 -10.6 -16.0 -13.0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 2.7 3.5 1.4 2.3 1.0 1.0 0 0 0 0 0.9 0
Peroxisomes 2.0 1.7 0.7 3.3 3.2 3.1 2.3 1.2 4.8 0 0 0 0 1.3 -0.8
SpindlePole 0 0 0 1.5 2.4 2.8 2.1 1.9 3.0 0 0 0 4.1 5.0 3.0
Vacuole 0 0.9 1.0 0.4 0 0 0 0 0.8 4.6 4.5 5.2 3.1 4.7 4.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.8592 5.9309 5.5265 4.9572 5.0063 5.4714 3.7435 5.7568 5.1423 5.1502 4.9211 5.2809 3.7772 5.2678 4.5532 4.2358 3.8402 4.406
Actin 0.0411 0.018 0.025 0.0013 0.0068 0.0239 0.1025 0.0179 0.0141 0.0024 0.0173 0.0221 0.0216 0.0412 0.0368 0.0151 0.0084 0.0494
Bud 0.0002 0.0005 0.0021 0.0001 0 0.0002 0.0008 0.0004 0.0002 0.0001 0.0001 0.0001 0.0003 0.0003 0.0001 0.0006 0.0003 0.0002
Bud Neck 0.0005 0.0005 0.0008 0.0002 0.0002 0.0008 0.004 0.0062 0.0003 0.0001 0.0003 0.0008 0.0005 0.0005 0.0004 0.0004 0.0005 0.0019
Bud Periphery 0.0001 0.0002 0.0007 0.0001 0 0.0001 0.001 0.0004 0.0002 0 0 0.0001 0.0002 0.0001 0.0001 0.0006 0.0001 0.0003
Bud Site 0.0011 0.0042 0.0013 0.0001 0.0001 0.0004 0.0219 0.0017 0.0003 0.0002 0.0001 0.0004 0.0006 0.005 0.0004 0.0078 0.001 0.0004
Cell Periphery 0.0001 0 0.0001 0 0 0 0.0006 0.0003 0 0 0 0.0001 0.0001 0.0001 0 0.0002 0 0.0001
Cytoplasm 0.0078 0.0065 0.0028 0.0016 0.0024 0.0018 0.0033 0.0037 0.0034 0.0018 0.0017 0.0012 0.0106 0.0091 0.0092 0.0016 0.0069 0.0017
Cytoplasmic Foci 0.1285 0.1394 0.1166 0.0967 0.1012 0.0913 0.1271 0.1293 0.1152 0.1136 0.0761 0.0736 0.1049 0.1378 0.1075 0.08 0.1913 0.0902
Eisosomes 0.0001 0 0 0 0 0 0.0002 0.0001 0.0001 0 0 0 0.0001 0 0.0001 0.0002 0 0.0001
Endoplasmic Reticulum 0.0026 0.0007 0.0004 0.0003 0.0003 0.0003 0.0014 0.0006 0.0022 0.0003 0.0005 0.0005 0.0055 0.0005 0.0013 0.0005 0.0015 0.0008
Endosome 0.2288 0.2404 0.2063 0.3439 0.236 0.1775 0.1962 0.2397 0.2504 0.2945 0.1656 0.187 0.2496 0.2085 0.2124 0.3027 0.2741 0.1676
Golgi 0.5209 0.5723 0.6178 0.5415 0.5817 0.6653 0.3886 0.5815 0.5698 0.5348 0.7331 0.6723 0.4093 0.5618 0.5776 0.4688 0.4596 0.6251
Lipid Particles 0.0169 0.0025 0.0038 0.0022 0.0054 0.0089 0.0519 0.0057 0.0081 0.0083 0.0013 0.0117 0.0424 0.0032 0.0039 0.0068 0.0219 0.0055
Mitochondria 0.0102 0.0044 0.0053 0.006 0.0027 0.0101 0.0154 0.0042 0.0087 0.0069 0.002 0.0083 0.0069 0.004 0.0091 0.034 0.0023 0.0245
None 0.0044 0.0001 0.0002 0 0.0047 0.0003 0.0018 0.0001 0.0008 0.0001 0 0 0.0157 0.0001 0.0117 0.0002 0.0042 0.0001
Nuclear Periphery 0.0012 0.0003 0.0001 0.0001 0.0069 0.0001 0.0137 0.0003 0.0016 0.0001 0 0.0001 0.0303 0.0002 0.0013 0.0001 0.0006 0.0002
Nucleolus 0.0004 0 0.0001 0 0.0007 0.0001 0.0012 0.0001 0 0 0 0 0.0007 0 0.0002 0.0002 0.0001 0
Nucleus 0.0005 0.0001 0.0001 0 0.0023 0.0001 0.0052 0.0001 0.0001 0 0 0 0.0093 0.0001 0.0009 0.0002 0.0001 0.0001
Peroxisomes 0.0284 0.0076 0.0143 0.0014 0.0038 0.0159 0.0512 0.0043 0.0183 0.0328 0.001 0.0188 0.0623 0.0212 0.0236 0.0755 0.0218 0.029
Punctate Nuclear 0.0018 0.0001 0.0001 0 0.0427 0.0013 0.0027 0.0003 0.0003 0.0004 0 0.0001 0.003 0.0001 0.0016 0.0002 0.0029 0.0002
Vacuole 0.0027 0.0012 0.0009 0.0017 0.0009 0.0006 0.0045 0.0019 0.0027 0.0017 0.0002 0.0009 0.0125 0.0033 0.0009 0.0021 0.0008 0.0009
Vacuole Periphery 0.0017 0.0011 0.001 0.0025 0.0012 0.001 0.005 0.0013 0.0033 0.0019 0.0006 0.0017 0.0135 0.0029 0.001 0.0021 0.0014 0.0015

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.1574 31.3639 30.5953 38.1968 33.7336 27.9737 31.8901 34.7505 35.3375 38.1023
Translational Efficiency 0.9632 0.6973 0.7972 0.857 0.7211 0.907 0.725 0.5484 0.7406 0.7208

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
26 621 1513 240 1590 890 2197 1981 1616 1511 3710 2221

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1179.76 1047.31 1473.86 1382.21 805.25 1086.40 1200.32 1173.17 811.28 1070.33 1311.87 1195.76
Standard Deviation 154.19 182.72 193.37 222.92 119.62 162.61 163.48 196.25 129.16 172.24 221.69 209.61
Intensity Change Log 2 — -0.171805 0.321106 0.228483 — 0.432047 0.575910 0.542903 — 0.104218 0.429950 0.364392

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.009863 0.014241 0.009265 0.021894 0.028582 0.002169 0.004477 0.020730 0.028281 0.007131 0.006430 0.020855
Bud Neck 0.001179 0.000427 0.000796 0.001877 0.000301 0.000118 0.000137 0.000181 0.000315 0.000245 0.000406 0.000364
Bud Site 0.005089 0.002836 0.001692 0.034024 0.003717 0.001192 0.000775 0.005010 0.003739 0.001868 0.001149 0.008145
Cell Periphery 0.000174 0.000096 0.000111 0.000483 0.000176 0.000052 0.000040 0.000175 0.000176 0.000070 0.000069 0.000209
Cytoplasm 0.001668 0.000889 0.000658 0.008955 0.002105 0.000652 0.000419 0.002134 0.002098 0.000750 0.000517 0.002871
Cytoplasmic Foci 0.232250 0.228265 0.077141 0.216766 0.190977 0.224459 0.147125 0.106171 0.191641 0.226023 0.118584 0.118122
Eisosomes 0.000070 0.000077 0.000064 0.000067 0.000228 0.000030 0.000041 0.000126 0.000225 0.000049 0.000051 0.000120
Endoplasmic Reticulum 0.001102 0.000801 0.001722 0.000929 0.000934 0.000374 0.000521 0.001212 0.000936 0.000550 0.001011 0.001181
Endosome 0.223088 0.188051 0.060656 0.219936 0.220409 0.192905 0.183070 0.151254 0.220452 0.190910 0.133147 0.158676
Golgi 0.440863 0.524337 0.780624 0.399204 0.484422 0.544584 0.618799 0.688564 0.483721 0.536263 0.684794 0.657296
Lipid Particles 0.066564 0.019248 0.025205 0.009648 0.027454 0.006157 0.013673 0.007813 0.028083 0.011537 0.018376 0.008011
Mitochondria 0.000870 0.004837 0.001626 0.000564 0.021558 0.007285 0.003538 0.002724 0.021225 0.006279 0.002758 0.002491
Mitotic Spindle 0.004735 0.002642 0.002135 0.017327 0.001035 0.001343 0.001078 0.000907 0.001094 0.001877 0.001509 0.002681
None 0.000009 0.000027 0.000033 0.000018 0.000110 0.000013 0.000012 0.000020 0.000109 0.000019 0.000021 0.000020
Nuclear Periphery 0.000027 0.000027 0.000564 0.000114 0.000025 0.000031 0.000161 0.000019 0.000026 0.000030 0.000325 0.000029
Nuclear Periphery Foci 0.000226 0.000247 0.002078 0.001469 0.000293 0.000237 0.001042 0.000206 0.000292 0.000241 0.001464 0.000343
Nucleolus 0.000020 0.000032 0.000005 0.000010 0.000133 0.000023 0.000004 0.000003 0.000131 0.000027 0.000004 0.000004
Nucleus 0.000037 0.000034 0.000044 0.000039 0.000346 0.000039 0.000007 0.000013 0.000341 0.000037 0.000022 0.000016
Peroxisomes 0.002331 0.004368 0.000377 0.013301 0.012483 0.002258 0.000647 0.001494 0.012320 0.003125 0.000537 0.002770
Vacuole 0.007536 0.004485 0.019913 0.047131 0.002016 0.006800 0.014125 0.006409 0.002105 0.005848 0.016485 0.010809
Vacuole Periphery 0.002298 0.004032 0.015292 0.006245 0.002696 0.009278 0.010307 0.004834 0.002689 0.007122 0.012340 0.004986

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.71 0.10 -1.55 -1.28 -2.29 11.04 9.73 2.46 -8.57 -7.19 8.19 9.00 2.42 -6.02 -6.86
Bud Neck 0.86 0.43 -0.90 -3.89 -2.89 3.93 2.96 2.47 -2.08 -0.94 0.82 -1.03 -1.04 -1.56 0.34
Bud Site 0.79 1.23 -5.25 -6.24 -6.49 3.66 4.29 -1.40 -5.73 -6.42 2.54 3.80 -4.39 -7.28 -8.50
Cell Periphery 0.61 0.49 -1.04 -1.42 -1.37 5.91 6.81 0.02 -7.75 -9.29 5.14 5.36 -0.88 -4.20 -4.29
Cytoplasm 0.78 0.76 -2.95 -3.36 -3.34 2.90 3.21 0.01 -3.89 -4.20 2.74 2.80 -1.39 -4.95 -4.78
Cytoplasmic Foci 0.11 4.35 0.44 1.00 -12.71 -5.25 9.74 20.82 19.89 10.62 -6.58 18.58 17.70 22.68 0.16
Eisosomes -0.20 0.16 0.09 0.77 -0.18 13.82 12.92 5.85 -9.28 -8.06 12.34 12.26 6.34 -7.32 -7.20
Endoplasmic Reticulum 0.74 -1.50 0.37 -0.54 3.03 3.45 2.61 -1.11 -4.96 -4.14 2.48 -0.30 -1.02 -4.12 -1.07
Endosome 1.22 5.78 0.15 -2.70 -16.45 4.12 6.68 13.11 6.85 6.51 5.10 17.94 12.00 6.40 -6.44
Golgi -1.66 -6.83 0.92 6.28 19.82 -6.50 -17.46 -27.31 -15.58 -9.15 -6.63 -29.75 -22.71 -14.93 4.12
Lipid Particles 1.34 1.18 1.60 2.95 5.48 7.39 4.93 7.50 -1.01 3.92 5.79 3.50 7.63 2.25 7.59
Mitochondria -2.51 -1.01 0.41 3.00 3.49 5.77 8.72 9.22 2.85 0.96 6.77 9.35 9.38 3.25 0.43
Mitotic Spindle 0.50 0.64 -2.55 -4.18 -4.45 -0.79 -0.38 0.35 1.10 0.70 -1.39 -1.17 -3.31 -1.39 -2.24
None -1.78 -5.25 -1.65 0.78 3.08 2.66 2.70 2.47 -1.53 -2.30 2.50 2.46 2.47 -0.24 0.21
Nuclear Periphery -0.06 -5.59 -3.34 -3.41 4.49 -0.62 -5.70 1.04 1.89 6.19 -0.53 -7.15 -0.57 -0.01 7.11
Nuclear Periphery Foci -0.21 -5.61 -3.58 -3.58 1.16 0.46 -2.16 0.72 0.32 2.70 0.47 -4.37 -0.27 -1.52 4.86
Nucleolus -0.48 1.11 0.65 1.03 -3.09 1.44 1.72 1.75 1.03 0.86 1.41 1.72 1.74 1.61 0.65
Nucleus 0.07 -0.39 -0.33 -0.60 0.22 2.05 2.27 2.25 0.86 -0.76 2.08 2.14 2.23 1.06 0.67
Peroxisomes -1.19 1.65 -3.99 -3.21 -5.22 8.13 9.72 8.83 1.75 -2.80 7.01 9.85 7.65 0.56 -5.86
Vacuole 0.87 -3.39 -6.06 -7.52 -4.82 -5.62 -12.39 -6.01 0.29 6.78 -5.76 -17.84 -9.25 -4.91 4.71
Vacuole Periphery -1.77 -12.35 -3.29 -1.75 6.97 -4.91 -10.11 -4.32 3.22 6.67 -5.07 -16.07 -4.90 2.32 11.04
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Delta adaptin-like subunit of the clathrin associated protein complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; suppressor of loss of casein kinase 1 function; the clathrin associated protein complex is also known as AP-3
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Apl5

Apl5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Apl5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available