ORF
Human Ortholog
Description Putative protein of unknown function; predicted to be palmitoylated
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0.06 0 0.05 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.12 0.09 0.05 0.06 0.05 0.07 0 0.05
Cytoplasm 0.94 0.98 0.99 0.99 0.98 0.95 0.96 – 0.86 0.86 0.77 0.81 0.99 0.99 0.99 0.96 0.93 0.93 0.65 0.73 0.68 0.72 0.75 0.73
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.05 0.08 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.12 0 – 0.19 0.17 0.29 0.21 0 0 0 0 0 0 0.08 0.06 0.13 0.07 0.06 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 1 0 8 17 11 10 10 9
Bud 1 0 0 0 0 1 1 – 4 3 7 5 1 0 0 0 0 0 1 6 3 3 8 14
Bud Neck 0 3 20 10 18 8 15 – 11 18 11 11 1 1 1 5 3 2 4 7 3 5 10 7
Bud Site 0 0 0 0 0 1 0 – 0 0 2 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 7 10 4 3 1 8 – 2 0 4 2 11 11 5 14 24 16 7 21 15 21 12 16
Cytoplasm 117 376 334 275 350 303 374 – 319 334 322 307 349 387 366 233 184 171 95 272 200 208 258 246
Endoplasmic Reticulum 1 1 2 0 2 0 0 – 0 0 1 1 0 1 2 15 10 15 4 3 3 3 3 3
Endosome 0 1 1 0 0 0 2 – 0 1 2 0 0 1 1 2 1 1 3 2 2 3 2 4
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 3 2 2 3 3 1 0 0 0 2 2
Mitochondria 5 5 0 0 0 37 12 – 70 67 120 80 0 0 0 4 3 3 12 21 38 20 19 9
Nucleus 1 0 0 1 0 4 3 – 3 1 2 1 0 1 1 2 1 1 0 0 0 1 1 1
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 1 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0
SpindlePole 0 0 0 3 5 3 14 – 11 15 14 18 0 1 0 1 2 1 0 1 0 0 3 3
Vac/Vac Membrane 0 0 0 1 1 0 1 – 4 5 1 2 0 0 0 1 2 4 1 4 0 2 3 8
Unique Cell Count 124 382 339 278 357 318 391 373 390 420 377 351 391 370 243 198 184 148 372 292 291 346 337
Labelled Cell Count 126 393 367 294 379 358 430 425 444 487 431 363 406 378 280 234 218 148 372 292 291 346 337


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.9 3.9 4.6 5.0 5.0 3.4 4.2 – 3.6 3.8 3.8 3.6 4.9 5.2 5.3 5.6 6.2 6.3 4.0 4.4 4.5
Std Deviation (1e-4) 1.4 0.6 1.1 5.7 1.7 1.0 1.7 – 1.4 1.3 1.3 0.8 1.2 1.7 2.1 1.6 1.9 2.8 1.5 1.9 1.9
Intensity Change (Log2) – – – 0.13 0.12 -0.43 -0.13 – -0.35 -0.27 -0.29 -0.35 0.09 0.17 0.19 0.28 0.43 0.44 -0.2 -0.05 -0.04

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.7919 -0.5968 -0.3927 -0.1542 -0.342 -0.6751 0.9596 0.9496 1.361 0.98 1.0942 0.927 3.0128 3.8162 3.208 2.9096 3.929 3.3816
Actin 0.03 0.0131 0.0342 0.0213 0.0094 0.033 0.0256 0.0017 0.0075 0.0082 0.0161 0.0141 0.0064 0.0017 0.0022 0.0017 0.0039 0.0047
Bud 0.0027 0.006 0.0013 0.0033 0.0012 0.0027 0.001 0.0194 0.0012 0.0007 0.0006 0.0004 0.0003 0.0007 0.0015 0.0004 0.0006 0.001
Bud Neck 0.0041 0.0082 0.0176 0.0087 0.0131 0.0331 0.0009 0.0023 0.0023 0.0022 0.002 0.019 0.0059 0.0042 0.005 0.0178 0.0069 0.0156
Bud Periphery 0.0079 0.0085 0.0032 0.0078 0.006 0.012 0.0062 0.0069 0.0021 0.0024 0.0014 0.0031 0.0019 0.0024 0.0059 0.0025 0.007 0.0082
Bud Site 0.0097 0.1009 0.0314 0.0221 0.0089 0.0033 0.0058 0.0521 0.0239 0.01 0.002 0.0012 0.0153 0.0757 0.0407 0.0054 0.0045 0.0018
Cell Periphery 0.0523 0.0446 0.0427 0.0601 0.0261 0.0286 0.0723 0.0579 0.0485 0.0343 0.0365 0.0549 0.1221 0.0668 0.0848 0.0822 0.0424 0.0584
Cytoplasm 0.3534 0.3743 0.4269 0.353 0.4835 0.4761 0.4589 0.5234 0.4504 0.5536 0.4088 0.5492 0.4943 0.5098 0.4912 0.6413 0.4535 0.5551
Cytoplasmic Foci 0.0285 0.0091 0.0149 0.0179 0.0238 0.0175 0.0282 0.0042 0.0204 0.0144 0.0145 0.008 0.0136 0.0036 0.0027 0.0021 0.0047 0.0035
Eisosomes 0.0124 0.0074 0.0029 0.0013 0.0017 0.0014 0.0014 0.0013 0.0009 0.0034 0.008 0.0006 0.0044 0.0015 0.0015 0.0006 0.0014 0.0006
Endoplasmic Reticulum 0.0072 0.0038 0.0079 0.0109 0.0047 0.0042 0.0115 0.0061 0.0026 0.0047 0.0066 0.0019 0.0054 0.006 0.0038 0.0037 0.0055 0.0024
Endosome 0.0189 0.0005 0.0126 0.0076 0.041 0.0031 0.0415 0.0011 0.0268 0.007 0.0132 0.0037 0.0043 0.0014 0.0004 0.0002 0.0005 0.0007
Golgi 0.0065 0.0005 0.0039 0.0076 0.017 0.0033 0.0153 0.0002 0.0096 0.0055 0.0026 0.0171 0.0012 0.0004 0.0004 0.0003 0.0005 0.0003
Lipid Particles 0.0109 0.0015 0.0043 0.0165 0.0781 0.0036 0.0078 0.0012 0.0039 0.024 0.0046 0.0109 0.0032 0.0015 0.0009 0.0005 0.0009 0.0006
Mitochondria 0.0085 0.0003 0.0018 0.0033 0.0182 0.005 0.0048 0.0009 0.0028 0.0024 0.0019 0.0015 0.0003 0.0003 0.0002 0.0001 0.0002 0.0002
None 0.422 0.401 0.3642 0.3768 0.1482 0.3535 0.2857 0.3152 0.3448 0.3127 0.4397 0.2986 0.3132 0.3184 0.3538 0.2391 0.4622 0.3428
Nuclear Periphery 0.0064 0.0003 0.0021 0.0033 0.0014 0.0007 0.0144 0.0003 0.0084 0.0015 0.0142 0.0001 0.0003 0.0004 0.0002 0.0002 0.0003 0.0003
Nucleolus 0.0011 0.0055 0.0064 0.0016 0.0398 0.0099 0.0006 0.0005 0.0143 0.0023 0.0021 0.0001 0.0009 0.0005 0.0004 0.0001 0.0004 0.0003
Nucleus 0.0032 0.0106 0.0061 0.0478 0.0576 0.0046 0.0037 0.0012 0.0055 0.0011 0.0057 0.0003 0.0006 0.0011 0.0007 0.0008 0.001 0.0006
Peroxisomes 0.0042 0.0003 0.0044 0.0203 0.0091 0.0014 0.0084 0.0001 0.008 0.0049 0.0009 0.0136 0.0006 0.0001 0.0001 0 0.0001 0.0002
Punctate Nuclear 0.0046 0.001 0.0021 0.0029 0.0044 0.0007 0.0018 0.0006 0.0084 0.0017 0.0159 0.0002 0.0008 0.0006 0.0003 0.0002 0.0004 0.0006
Vacuole 0.0045 0.0024 0.0082 0.0054 0.0058 0.0021 0.0031 0.0032 0.0059 0.0026 0.0019 0.0014 0.0048 0.003 0.0032 0.0011 0.003 0.002
Vacuole Periphery 0.0012 0.0001 0.0006 0.0005 0.0009 0.0003 0.0011 0.0001 0.0018 0.0004 0.0009 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 26.7076 36.8356 53.6549 53.9531 46.4998 19.8289 37.9342 47.0164 43.9816 51.6035
Translational Efficiency 2.44 2.1731 1.628 1.165 1.5962 3.3402 1.8522 1.4033 1.7008 1.6795

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
56 1415 2226 2291 2433 2162 1108 1481 2489 3577 3334 3772

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 632.39 753.25 767.49 706.93 650.69 750.35 784.55 738.02 650.28 751.50 773.16 719.14
Standard Deviation 73.32 90.67 84.52 81.95 69.17 95.74 91.48 93.35 69.32 93.77 87.27 87.93
Intensity Change Log 2 — 0.252314 0.279333 0.160753 — 0.205593 0.269895 0.181690 — 0.228810 0.274555 0.171408

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000520 0.001082 0.000123 0.000254 0.000392 0.000694 0.000108 0.000198 0.000395 0.000848 0.000118 0.000232
Bud Neck 0.032743 0.040236 0.005514 0.010099 0.023668 0.047017 0.003431 0.003641 0.023872 0.044335 0.004822 0.007564
Bud Site 0.006140 0.024679 0.009194 0.022557 0.003531 0.029803 0.003917 0.007673 0.003590 0.027776 0.007440 0.016713
Cell Periphery 0.000547 0.000611 0.000295 0.000374 0.000412 0.000755 0.000345 0.000332 0.000415 0.000698 0.000312 0.000358
Cytoplasm 0.368696 0.456210 0.392669 0.544996 0.495255 0.535169 0.441335 0.555060 0.492407 0.503934 0.408843 0.548948
Cytoplasmic Foci 0.341357 0.261084 0.012916 0.032457 0.148744 0.117403 0.035689 0.034462 0.153078 0.174241 0.020484 0.033244
Eisosomes 0.001752 0.000800 0.000039 0.000094 0.001095 0.000821 0.000097 0.000074 0.001110 0.000813 0.000058 0.000086
Endoplasmic Reticulum 0.000465 0.001637 0.001427 0.000837 0.001014 0.000723 0.001523 0.000685 0.001001 0.001085 0.001459 0.000777
Endosome 0.019564 0.017926 0.001261 0.002350 0.003967 0.007774 0.002216 0.001641 0.004318 0.011790 0.001578 0.002072
Golgi 0.004746 0.007586 0.000070 0.000371 0.002740 0.003482 0.000089 0.000201 0.002786 0.005105 0.000076 0.000304
Lipid Particles 0.046001 0.007267 0.000849 0.001415 0.008788 0.004731 0.002160 0.001123 0.009625 0.005734 0.001285 0.001300
Mitochondria 0.012186 0.005567 0.000612 0.000893 0.003034 0.004642 0.000226 0.000357 0.003240 0.005008 0.000484 0.000682
Mitotic Spindle 0.000252 0.001858 0.001180 0.005826 0.000862 0.005407 0.000497 0.001540 0.000848 0.004003 0.000953 0.004143
None 0.003848 0.001983 0.003114 0.003229 0.002269 0.003171 0.006036 0.012371 0.002304 0.002701 0.004085 0.006819
Nuclear Periphery 0.000413 0.000160 0.000987 0.000701 0.000232 0.000205 0.000983 0.000649 0.000237 0.000188 0.000986 0.000681
Nuclear Periphery Foci 0.000428 0.000494 0.000308 0.000445 0.000250 0.000229 0.000914 0.000375 0.000254 0.000334 0.000510 0.000418
Nucleolus 0.002214 0.000704 0.000337 0.000475 0.000553 0.000762 0.000486 0.000322 0.000590 0.000739 0.000386 0.000415
Nucleus 0.080709 0.097384 0.545387 0.309723 0.267872 0.190477 0.439054 0.319224 0.263661 0.153651 0.510049 0.313454
Peroxisomes 0.026027 0.011320 0.000227 0.000614 0.005067 0.005861 0.000575 0.000538 0.005538 0.008021 0.000343 0.000585
Vacuole 0.050401 0.059541 0.023258 0.061969 0.029838 0.039781 0.060236 0.059434 0.030301 0.047598 0.035547 0.060974
Vacuole Periphery 0.000994 0.001870 0.000234 0.000318 0.000418 0.001090 0.000086 0.000100 0.000431 0.001399 0.000184 0.000233

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.61 2.25 1.45 5.59 -1.96 -2.74 4.53 2.53 4.40 -0.52 -4.79 4.84 2.48 6.83 -1.93
Bud Neck -0.98 3.57 3.00 11.27 -3.99 -8.48 13.10 13.45 18.04 -0.59 -9.13 12.90 10.87 20.09 -3.67
Bud Site -7.28 -1.39 -5.33 1.60 -4.94 -12.19 -0.51 -2.33 9.21 -1.66 -16.17 -4.31 -8.57 6.49 -4.90
Cell Periphery -0.48 1.98 1.50 4.76 -2.05 -7.72 4.47 3.19 8.27 0.87 -8.06 5.45 3.64 9.85 -0.96
Cytoplasm -2.77 -0.41 -4.83 -7.34 -17.15 -5.70 11.28 -0.79 3.69 -10.21 -1.85 16.88 -3.42 -1.61 -19.83
Cytoplasmic Foci 3.11 12.90 12.16 40.05 -12.82 6.89 30.71 32.17 23.95 0.01 -4.67 39.50 35.41 43.06 -9.69
Eisosomes 1.04 1.90 1.84 7.72 -6.32 2.55 12.01 12.36 10.33 4.85 3.00 12.63 12.33 12.80 -4.47
Endoplasmic Reticulum -5.29 -5.62 -4.49 3.15 3.42 2.28 -8.04 -1.08 -3.84 7.90 -0.64 -5.59 -0.58 0.24 6.14
Endosome 0.39 4.45 4.24 12.19 -2.15 -6.36 4.95 6.85 10.62 3.11 -11.32 7.98 6.76 15.52 -0.92
Golgi -2.00 3.75 3.53 11.70 -2.59 -1.37 9.11 8.66 7.23 -1.26 -4.95 9.46 8.59 12.94 -2.87
Lipid Particles 2.38 2.77 2.75 13.00 -2.48 5.44 10.85 13.17 7.33 7.49 5.15 12.10 12.12 12.59 0.70
Mitochondria 0.86 1.50 1.47 6.00 -1.25 -1.93 5.36 5.14 6.60 -1.20 -2.40 5.07 4.78 8.64 -1.27
Mitotic Spindle -2.52 -2.85 -4.87 -3.18 -3.97 -3.83 1.00 -2.14 2.54 -3.11 -3.91 -0.28 -4.48 -0.49 -4.63
None 0.75 0.42 0.38 -2.61 -0.32 -2.08 -4.66 -5.63 -4.76 -3.14 -1.23 -4.72 -5.82 -4.86 -3.27
Nuclear Periphery 2.01 -5.24 -3.30 -17.09 5.00 1.13 -22.56 -8.71 -8.86 3.16 2.74 -34.33 -15.34 -16.32 5.19
Nuclear Periphery Foci -0.30 0.50 -0.14 0.30 -1.34 0.36 -9.03 -5.45 -6.39 6.29 -2.08 -7.56 -4.15 -2.97 2.33
Nucleolus 1.87 2.30 2.05 0.93 -0.94 -1.79 1.48 4.01 3.71 2.60 -1.67 3.64 1.24 2.28 -0.54
Nucleus -1.27 -33.77 -17.40 -34.56 28.47 13.16 -20.06 -9.41 -19.13 10.63 21.90 -39.42 -10.84 -33.64 29.35
Peroxisomes 1.44 2.56 2.53 11.61 -1.71 -1.13 9.01 9.61 9.25 0.11 -3.54 10.26 9.77 14.65 -1.28
Vacuole -0.83 1.95 -2.75 -6.14 -16.65 -5.71 -14.03 -16.02 -13.09 0.33 -10.80 -9.57 -22.63 -14.98 -11.78
Vacuole Periphery -1.87 3.35 3.10 3.73 -0.74 -2.41 2.78 2.76 3.94 0.02 -3.83 1.93 1.71 5.17 -0.57
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; predicted to be palmitoylated
Localization
Cell Percentages cytoplasm (28%), ER (2%), mixed (52%)
Cell Cycle Regulation No
Subcompartmental Group N/A

YPL199C

YPL199C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ypl199c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available