Standard name
Human Ortholog
Description Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.94 0.97 0.96 0.95 0.92 0.78 0.76 0.69 0.67 0.63 0.63 0.55 0.99 1.0 0.99 0.91 0.93 0.89 0.65 0.85 0.73 0.87 0.85 0.72
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.06 0.07 0.06 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0.11 0.43 0.42 0.39 0.5 0.53 0.52 0.58 0 0 0 0 0 0 0.14 0.06 0.15 0 0.05 0.09
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.06 0 0.06 0 0.05 0 0 0 0.07 0.13 0.06 0.05 0 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 1 1 1 0 1 0 0 0 0 1 0 1 2 7 0 2 1
Bud 1 1 2 3 1 6 4 5 9 14 7 7 0 0 0 2 1 1 4 3 3 0 3 2
Bud Neck 3 0 0 1 0 2 1 0 1 0 0 0 0 0 0 0 0 0 1 1 0 0 0 2
Bud Site 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 4 1 1 2 4 5 1 3 4 7 2 6 0 1 0 7 8 5 1 1 2 0 0 0
Cytoplasm 218 270 340 243 249 296 348 343 283 307 133 123 149 220 184 304 235 213 173 240 249 84 160 84
Endoplasmic Reticulum 0 1 1 1 0 5 2 10 7 3 5 5 0 1 1 21 14 17 15 0 3 0 2 1
Endosome 3 0 3 1 3 2 0 6 0 2 0 0 0 0 0 9 3 4 3 2 4 0 0 1
Golgi 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 1 1 0 2 0
Mitochondria 6 6 14 19 29 162 193 197 211 258 110 128 0 4 2 14 3 10 37 18 52 3 10 10
Nucleus 1 0 0 1 0 1 4 3 2 2 1 1 1 0 0 0 2 2 0 0 0 0 1 0
Nuclear Periphery 0 0 0 0 2 0 0 2 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 1 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0
Peroxisomes 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 3 1 0 1 1 0 2 3 1 3 1 1 0 0 0 1 0 1 3 3 6 0 0 1
Vac/Vac Membrane 4 1 0 2 4 10 9 32 14 29 5 11 1 0 0 22 32 15 14 4 4 0 1 7
Unique Cell Count 232 277 353 256 271 380 459 499 425 486 210 222 151 221 185 334 254 238 268 284 342 97 190 118
Labelled Cell Count 244 282 363 275 294 490 564 605 534 631 265 283 151 226 187 381 299 269 268 284 342 97 190 118


Cytoplasm, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.7 4.0 3.8 3.9 4.3 3.9 3.7 4.4 4.4 4.3 4.4 4.7 4.6 4.6 4.8 6.6 7.6 7.4 4.0 4.5 5.3
Std Deviation (1e-4) 1.0 0.9 1.2 1.5 1.4 1.5 1.2 1.3 1.7 1.4 1.7 1.6 1.9 1.9 2.0 1.9 2.1 2.4 1.6 2.3 2.1
Intensity Change (Log2) – – – 0.01 0.17 0.02 -0.06 0.21 0.22 0.16 0.2 0.3 0.26 0.28 0.34 0.79 0.99 0.96 0.06 0.23 0.47


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 4.9 6.9 4.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.4004 0.1406 0.3328 -0.0718 0.387 0.0964 1.1333 1.5088 1.1912 0.9135 1.1146 1.2195 1.7292 1.8692 2.0383 1.6883 1.351 1.9172
Actin 0.0028 0.0004 0.0215 0.0682 0.0003 0.0004 0.0213 0.001 0.0041 0.0003 0.0014 0.001 0.009 0.0032 0.0149 0.0012 0 0.0002
Bud 0.0091 0.0006 0.0012 0.0016 0 0.0001 0.0012 0.0006 0.0003 0.0001 0.0001 0.002 0.0011 0.0003 0.0002 0.0002 0.0001 0
Bud Neck 0.0192 0.0015 0.0034 0.0003 0.0001 0.0012 0.0015 0.0003 0.0003 0 0.0001 0.0006 0.0004 0.0003 0.0017 0.0001 0.0001 0.0001
Bud Periphery 0.0319 0.0008 0.0031 0.0018 0 0.0002 0.0032 0.001 0.0014 0.0001 0.0001 0.0032 0.0025 0.0008 0.0002 0.0003 0.0001 0
Bud Site 0.006 0.0328 0.0195 0.0132 0 0.0001 0.0058 0.0059 0.0013 0 0.0012 0.0002 0.0013 0.0206 0.0103 0.0002 0.0002 0
Cell Periphery 0.0036 0.0006 0.0018 0.0002 0 0.0001 0.0003 0.0002 0.0004 0 0 0.0002 0.0003 0.0027 0.0002 0.0001 0 0
Cytoplasm 0.0926 0.1595 0.1114 0.0776 0.1777 0.1506 0.0151 0.0249 0.025 0.0256 0.0258 0.0647 0.0206 0.1792 0.09 0.0385 0.0926 0.0688
Cytoplasmic Foci 0.0061 0.004 0.0092 0.0044 0.0027 0.027 0.0232 0.0106 0.0089 0.0011 0.0151 0.009 0.0109 0.0027 0.0141 0.0027 0.0092 0.0015
Eisosomes 0.0002 0.0001 0.0013 0.0001 0.0002 0.0001 0.0009 0.0004 0.0004 0.0002 0.0001 0.0001 0.0007 0.0006 0.0002 0 0 0.0001
Endoplasmic Reticulum 0.0067 0.0016 0.0031 0.0009 0.0003 0.001 0.0013 0.0004 0.0028 0.0003 0.0004 0.0006 0.0041 0.0011 0.0013 0.0009 0.0014 0.0003
Endosome 0.0106 0.0008 0.0029 0.0009 0.0005 0.0099 0.0131 0.0007 0.0198 0.0002 0.0463 0.0025 0.0545 0.0005 0.0048 0.0405 0.046 0.0011
Golgi 0.0007 0.0002 0.0016 0.0014 0.0001 0.0015 0.0047 0.0009 0.0034 0 0.0204 0.0037 0.0049 0.0003 0.006 0.0368 0.0004 0.0019
Lipid Particles 0.0006 0.0003 0.0102 0.0005 0.0002 0.0035 0.0175 0.002 0.0036 0.0001 0.0102 0.0005 0.0087 0.0002 0.0072 0.0002 0.0001 0.0008
Mitochondria 0.0035 0.0002 0.0059 0.0007 0.0005 0.002 0.0089 0.0014 0.0027 0.0002 0.0055 0.0005 0.0093 0.0008 0.0011 0.0397 0.0005 0.0158
None 0.6386 0.7937 0.7802 0.8259 0.815 0.7971 0.8212 0.9313 0.9103 0.9695 0.8314 0.9063 0.8171 0.7852 0.8281 0.8358 0.8136 0.9078
Nuclear Periphery 0.0208 0.0004 0.0009 0.0003 0.0003 0.0003 0.0035 0.0001 0.0023 0.0005 0.0003 0.0003 0.0085 0.0002 0.0003 0.0002 0.0011 0.0001
Nucleolus 0.003 0.0002 0.0088 0.0001 0.0002 0.0001 0.0015 0.0002 0.0006 0.0001 0.0002 0.0001 0.0029 0.0001 0.0006 0 0.0002 0
Nucleus 0.1096 0.0009 0.0028 0.0003 0.0005 0.0004 0.0017 0.0004 0.0005 0.0005 0.0004 0.0005 0.0041 0.0003 0.0004 0.0001 0.002 0.0001
Peroxisomes 0.0004 0.0002 0.0043 0.0007 0.0002 0.0012 0.0403 0.0165 0.0037 0.0001 0.0299 0.001 0.0042 0.0001 0.0174 0.0001 0.0001 0.0011
Punctate Nuclear 0.0038 0.0007 0.0027 0.0004 0.0008 0.0007 0.0122 0.0011 0.0016 0.0009 0.0004 0.0021 0.016 0.0001 0.0005 0.0001 0.0002 0.0001
Vacuole 0.0249 0.0006 0.0037 0.0004 0.0002 0.0021 0.0011 0.0002 0.0055 0.0002 0.0098 0.0007 0.0136 0.0005 0.0006 0.0011 0.0283 0.0001
Vacuole Periphery 0.0054 0.0001 0.0005 0.0001 0.0001 0.0004 0.0005 0 0.001 0 0.0008 0.0001 0.0054 0 0.0001 0.0014 0.0038 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.277 14.586 11.2744 15.5141 14.5441 16.3075 17.974 16.5897 17.2111 15.7228
Translational Efficiency 0.4791 0.5338 0.7239 0.5331 0.4863 0.6445 0.7453 0.7343 0.625 0.6156

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1124 1506 82 1329 1879 1813 184 130 3003 3319 266 1459

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 627.01 649.17 4550.58 823.18 676.42 719.98 1000.53 918.61 657.93 687.85 2094.91 831.68
Standard Deviation 66.40 87.83 1437.92 130.41 78.99 97.35 226.26 138.15 78.27 99.60 1833.09 133.91
Intensity Change Log 2 — 0.050108 2.859490 0.392719 — 0.090038 0.564773 0.441533 — 0.070967 2.090463 0.418258

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000193 0.000352 0.000407 0.001618 0.000277 0.000576 0.000410 0.000455 0.000245 0.000475 0.000409 0.001515
Bud Neck 0.017428 0.046418 0.008595 0.011044 0.014843 0.051595 0.001824 0.001841 0.015810 0.049246 0.003911 0.010224
Bud Site 0.005990 0.015730 0.009696 0.037681 0.003074 0.024153 0.008045 0.054342 0.004165 0.020331 0.008554 0.039166
Cell Periphery 0.000178 0.000132 0.009726 0.000197 0.000110 0.000208 0.000443 0.000107 0.000135 0.000173 0.003305 0.000189
Cytoplasm 0.498801* 0.355561* 0.502427* 0.492970* 0.486482* 0.350855* 0.429210* 0.583537* 0.491093* 0.352990* 0.451781* 0.501040*
Cytoplasmic Foci 0.248845* 0.249376* 0.069936 0.020978 0.228703* 0.302561* 0.042858 0.006655 0.236242* 0.278428* 0.051206 0.019702
Eisosomes 0.000212 0.000134 0.000007 0.000047 0.000146 0.000195 0.000091 0.000027 0.000170 0.000167 0.000065 0.000045
Endoplasmic Reticulum 0.000944 0.001002 0.000206 0.001807 0.000749 0.000644 0.003588 0.001225 0.000822 0.000806 0.002545 0.001755
Endosome 0.012665 0.037024 0.003362 0.003803 0.008510 0.032250 0.007314 0.005977 0.010065 0.034416 0.006095 0.003997
Golgi 0.002031 0.006353 0.045570 0.000684 0.001871 0.008859 0.003748 0.000398 0.001931 0.007722 0.016640 0.000658
Lipid Particles 0.012410 0.011343 0.015807 0.001172 0.009069 0.008940 0.004433 0.002913 0.010319 0.010031 0.007939 0.001327
Mitochondria 0.004888 0.022186 0.000264 0.003419 0.003501 0.021357 0.000175 0.000379 0.004020 0.021733 0.000203 0.003148
Mitotic Spindle 0.000151 0.005720 0.017882 0.027942 0.001096 0.011519 0.001817 0.015529 0.000742 0.008887 0.006769 0.026836
None 0.005002 0.004938 0.001516 0.010673 0.002717 0.001988 0.002282 0.013750 0.003572 0.003327 0.002046 0.010947
Nuclear Periphery 0.000442 0.000995 0.002227 0.001365 0.000491 0.000266 0.001260 0.000835 0.000472 0.000597 0.001558 0.001318
Nuclear Periphery Foci 0.000294 0.000431 0.016083 0.000909 0.000238 0.000332 0.006423 0.001144 0.000259 0.000377 0.009401 0.000930
Nucleolus 0.001620 0.003679 0.000220 0.000526 0.000857 0.001406 0.000462 0.000298 0.001142 0.002437 0.000387 0.000505
Nucleus 0.133159* 0.111533 0.063253 0.284321* 0.189832* 0.076703 0.295952* 0.185934* 0.168620* 0.092507 0.224218* 0.275554*
Peroxisomes 0.005435 0.017896 0.000071 0.002329 0.005323 0.024183 0.000407 0.000286 0.005365 0.021331 0.000303 0.002147
Vacuole 0.047990 0.104963 0.208064* 0.095152 0.041469 0.078378 0.188846 0.118887 0.043910 0.090441 0.194771 0.097266
Vacuole Periphery 0.001323 0.004233 0.024683 0.001364 0.000643 0.003034 0.000412 0.005481 0.000898 0.003578 0.007894 0.001731

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.48 -2.41 -2.20 -1.73 -1.11 -1.73 -0.96 -0.39 2.11 1.01 -2.05 -2.00 -2.05 -1.36 -1.40
Bud Neck -9.82 2.19 5.11 14.49 1.77 -13.98 12.34 7.92 18.27 -2.50 -17.21 9.65 6.66 21.35 -2.22
Bud Site -6.34 -2.25 -5.11 -1.34 -1.94 -12.81 -4.26 -2.33 1.03 -1.59 -14.51 -4.21 -6.51 0.50 -4.03
Cell Periphery 4.33 -6.77 2.20 -0.46 6.79 -2.33 -2.27 0.98 2.54 2.39 -1.57 -5.99 0.07 1.39 5.99
Cytoplasm 14.09 0.56 10.95 -2.73 2.83 15.30 6.04 4.76 -0.20 -0.04 20.67 5.23 12.63 -3.20 0.65
Cytoplasmic Foci -0.04 11.98 38.96 41.12 4.27 -9.88 31.29 41.53 49.74 5.43 -7.60 30.25 56.56 64.18 6.05
Eisosomes 4.87 13.51 9.96 12.16 -14.51 -4.67 3.86 9.17 12.55 3.43 0.43 10.05 14.81 18.08 2.07
Endoplasmic Reticulum -0.44 3.92 -10.39 -12.11 -18.37 0.88 -8.39 -5.98 -6.29 2.23 0.05 -7.01 -14.89 -15.76 -0.15
Endosome -10.97 7.23 10.22 17.19 1.23 -14.90 2.24 5.25 17.17 3.08 -18.42 5.88 12.98 25.89 4.88
Golgi -6.61 -6.63 7.52 9.79 6.94 -9.78 0.17 6.88 12.88 1.10 -11.74 -5.07 8.70 15.88 5.82
Lipid Particles 0.70 -1.55 8.38 11.33 4.86 0.13 6.70 3.65 3.52 0.62 0.36 1.56 13.43 14.70 5.70
Mitochondria -8.49 5.01 3.26 11.05 -2.61 -9.72 8.22 7.71 11.74 -3.12 -13.13 8.95 4.27 15.06 -2.90
Mitotic Spindle -5.15 -1.50 -7.43 -4.76 -0.41 -6.12 -0.57 -2.46 -0.73 -2.39 -7.64 -1.60 -7.49 -3.78 -3.38
None 0.11 3.55 -0.88 -1.12 -4.55 1.10 1.11 -3.94 -4.28 -4.28 0.41 3.12 -2.99 -3.41 -5.00
Nuclear Periphery -2.79 -4.49 -18.16 -7.26 -0.23 4.17 -9.57 -6.97 -7.87 -2.68 -1.33 -8.68 -20.88 -15.27 -3.66
Nuclear Periphery Foci -3.46 -7.93 -12.11 -9.03 7.42 -1.39 -7.71 -3.59 -3.25 4.79 -2.79 -10.50 -12.96 -9.35 9.21
Nucleolus -3.52 3.23 2.52 7.98 -2.64 -3.95 3.81 3.96 7.95 0.02 -5.13 4.43 3.18 9.28 -1.63
Nucleus 3.57 5.26 -22.83 -25.63 -19.69 21.97 -3.97 -1.63 -6.86 1.69 19.19 -2.76 -19.34 -30.24 -5.79
Peroxisomes -8.21 5.83 4.52 13.30 -2.12 -12.92 11.05 11.33 17.37 2.26 -15.36 11.50 7.97 20.46 -1.63
Vacuole -13.07 -6.57 -22.39 -13.06 0.51 -11.45 -12.36 -10.10 -8.78 -1.28 -17.71 -13.88 -25.65 -17.89 2.96
Vacuole Periphery -7.13 -4.83 2.69 8.62 5.02 -10.87 3.98 -0.43 2.06 -0.83 -12.46 -4.16 1.34 9.86 4.34
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
Localization
Cell Percentages cytoplasm (24%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Thi6

Thi6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Thi6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available