Standard name
Human Ortholog
Description Subunit 2 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.07 0 0 0 0.07 0 0.06 0.11 0.1
Bud 0 0 0 0.06 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.11 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0.11 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0.05 0 0 0 – 0 0 0 0 0.05 0.06 0.09 0.08 0.06 0 0 0 0 0 0.05
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0.2 0.09 0.31 0.17 0.16 0.17 0.08 0.13 0.06 0.1 0.12 0.13
Mitochondria 0.9 0.92 0.96 0.94 0.85 0.89 0.88 0.83 – 0.89 0.95 0.92 0.87 0.85 0.74 0.08 0.07 0.11 0.69 0.67 0.69 0.57 0.54 0.53
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.07 0.05 0.05 0 0.05 0.07 0.09 0 – 0.06 0.06 0 0 0 0 0 0.07 0 0 0 0 0 0 0
Nucleolus 0.05 0.05 0 0 0.06 0.1 0.17 0.19 – 0.11 0.12 0.11 0 0 0 0 0.08 0.06 0 0 0 0 0 0
Peroxisomes 0.05 0 0.11 0.1 0.06 0 0 0 – 0 0 0 0.06 0.14 0 0.36 0.33 0.38 0.11 0.07 0.18 0.19 0.14 0.09
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.08 0 0 0.07 0 0 0 – 0 0 0 0.12 0.09 0.15 0.12 0.12 0.13 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 2 0 0 3 2 4 – 0 0 1 7 2 1 8 3 3 6 9 4 18 35 32
Bud 1 0 9 13 20 26 18 20 – 13 18 9 4 7 2 5 4 10 0 0 0 1 1 5
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 4 0 0 8 3 7 – 10 5 3 0 0 0 1 0 0 – – – – – –
Cell Periphery 2 6 4 5 6 2 5 3 – 7 3 1 6 9 6 10 2 3 0 0 0 0 0 0
Cytoplasm 1 1 0 8 15 14 12 14 – 10 6 6 1 2 5 7 8 7 0 0 0 1 0 4
Endoplasmic Reticulum 4 3 3 1 1 4 1 3 – 1 1 1 1 0 0 3 4 2 0 0 0 2 2 3
Endosome 5 0 10 2 27 5 5 5 – 2 2 2 4 19 14 11 6 6 11 4 12 9 10 15
Golgi 7 1 3 0 2 0 0 1 – 0 1 4 40 32 71 20 12 16 21 19 21 28 40 42
Mitochondria 219 135 346 217 424 598 869 782 – 741 673 459 176 300 167 10 5 10 177 101 240 166 178 175
Nucleus 2 0 0 0 0 4 4 4 – 4 0 2 0 1 2 2 1 0 0 0 0 0 0 0
Nuclear Periphery 18 8 17 4 26 50 87 42 – 52 39 19 4 5 3 4 5 1 3 0 1 1 5 4
Nucleolus 11 8 14 4 31 64 164 180 – 91 86 55 2 7 3 4 6 6 0 0 0 0 1 3
Peroxisomes 12 1 40 22 31 16 13 29 – 25 6 4 13 48 9 44 25 36 29 10 63 55 46 30
SpindlePole 1 1 7 0 9 5 5 7 – 12 6 3 1 6 0 7 3 2 1 0 1 2 0 1
Vac/Vac Membrane 18 12 8 0 35 17 23 21 – 28 16 21 24 32 34 14 9 12 6 2 0 3 3 8
Unique Cell Count 244 146 359 231 500 670 993 940 834 709 499 203 351 227 121 76 94 259 153 350 295 329 333
Labelled Cell Count 301 176 467 276 627 816 1211 1122 996 862 590 283 470 317 150 93 114 259 153 350 295 329 333


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.4 8.9 6.6 7.1 8.0 9.3 9.8 11.5 – 13.0 14.6 15.3 10.6 10.6 10.4 10.2 9.7 10.5 13.6 15.8 17.3
Std Deviation (1e-4) 3.0 2.1 1.7 1.8 1.9 2.1 2.7 3.4 – 5.2 5.9 6.8 2.2 4.0 2.7 3.6 2.9 4.1 9.7 13.6 13.9
Intensity Change (Log2) – – – 0.1 0.28 0.49 0.56 0.8 – 0.97 1.14 1.21 0.68 0.68 0.65 0.62 0.55 0.67 1.03 1.25 1.39

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud 2.0 1.2 1.2 -0.8 -0.4 – -1.1 0 -0.7 0 -0.5 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 0 1.4 0 0 0 0
Cytoplasm 0 3.3 0 0 0 – 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Endosome 0 1.9 -2.6 0 0 – 0 0 -2.9 -0.6 1.8 2.0 2.9 0 0
Golgi 0 0 0 0 0 – 0 0 0 8.1 5.1 10.8 7.0 0 0
Mitochondria -1.4 -5.5 -4.0 -4.8 -6.3 – -4.2 -1.1 -2.6 -4.3 -5.1 -8.1 -19.2 -18.0 -18.0
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery -1.9 0.3 1.7 2.5 -0.2 – 1.0 0.5 -0.7 -1.7 -2.5 -2.2 -0.7 0 0
Nucleolus -1.5 1.5 3.3 6.1 6.9 – 3.9 4.4 3.8 -2.0 -1.5 -1.8 0 0 0
Peroxisomes -0.6 -2.6 -5.9 -8.2 -5.8 – -5.7 -7.8 -6.8 -1.8 1.0 -3.1 6.3 4.8 6.3
SpindlePole 0 -0.2 0 0 0 – -0.6 0 0 0 -0.2 0 0 0 0
Vacuole 0 3.2 0.3 0.1 0 – 1.0 0 1.6 4.7 4.0 5.8 4.2 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 17.0633 21.3716 19.4856 18.6228 18.1012 20.0735 22.6143 26.2378 24.1486 24.7 20.3343 24.51 24.5017 25.5831 24.6167 25.2521 24.9459 26.024
Actin 0.0241 0.0221 0.0129 0.004 0.0047 0.0078 0.0147 0.0023 0.0269 0.0354 0.0037 0.0045 0.0123 0.0086 0.0041 0.0136 0.0081 0.0009
Bud 0.0001 0.0001 0 0 0 0 0.0004 0 0.0001 0.0006 0 0.0001 0 0.0001 0 0.0001 0 0
Bud Neck 0.0001 0.0001 0 0 0 0 0.0005 0 0 0 0 0.0005 0.0001 0 0 0.0009 0 0
Bud Periphery 0.0003 0.0002 0 0 0.0001 0 0.0008 0 0.0001 0.0007 0.0001 0.0001 0 0.0001 0 0.0005 0 0
Bud Site 0.0004 0.0003 0 0.0001 0.0001 0 0.0019 0 0.0004 0.0012 0.0001 0.0004 0.0001 0.0001 0.0001 0.0001 0 0
Cell Periphery 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0.0003 0.0001 0 0.0001 0 0.0001 0.0001 0.0002 0.0001 0.0001 0 0
Cytoplasm 0 0 0 0 0 0 0.0006 0 0.0001 0 0 0 0.0001 0 0 0.0003 0 0
Cytoplasmic Foci 0.0041 0.0023 0.0007 0.0016 0.0028 0.0007 0.0044 0.0006 0.0024 0.0003 0.0005 0.0013 0.0008 0.0007 0.0024 0.0002 0.0001 0.0002
Eisosomes 0.0016 0.0017 0.0009 0.0005 0.0005 0.001 0.0011 0.0003 0.0012 0.0004 0.0005 0.0005 0.0008 0.0004 0.0007 0.0012 0.0005 0.0003
Endoplasmic Reticulum 0.0001 0 0 0 0.0001 0 0.0003 0 0.0002 0 0 0 0.0001 0 0 0.0023 0 0
Endosome 0.0038 0.0036 0.0017 0.0021 0.0085 0.0019 0.0037 0.0009 0.0074 0.001 0.0007 0.0013 0.0008 0.0015 0.0008 0.0033 0.0005 0.0003
Golgi 0.0505 0.0336 0.0156 0.0084 0.0314 0.0233 0.0044 0.0073 0.0074 0.0359 0.0036 0.0158 0.0048 0.0228 0.0087 0.0043 0.0064 0.0015
Lipid Particles 0.0352 0.0261 0.0117 0.0119 0.0417 0.0096 0.034 0.0078 0.0164 0.0012 0.0238 0.0168 0.0213 0.0119 0.0122 0.0022 0.004 0.0055
Mitochondria 0.8323 0.8849 0.9367 0.9559 0.8971 0.9416 0.8757 0.9696 0.9138 0.9185 0.9551 0.944 0.9397 0.9349 0.9564 0.945 0.9642 0.9853
None 0.0001 0 0 0 0 0 0.016 0 0.0002 0 0 0 0.0002 0 0.0001 0.0011 0 0
Nuclear Periphery 0.0005 0.0001 0 0.0001 0.0001 0 0.0009 0 0.0011 0 0 0.0001 0.0001 0.0001 0 0.0071 0 0.0001
Nucleolus 0.0005 0.0002 0.0001 0.0002 0.0001 0 0.0009 0.0001 0.0001 0 0.0001 0.0001 0.0002 0.0003 0.0004 0.0003 0 0
Nucleus 0.0002 0 0 0 0 0 0.0003 0 0.0001 0 0 0 0.0001 0.0002 0.0001 0.0016 0 0
Peroxisomes 0.0383 0.0162 0.0135 0.0106 0.0099 0.0105 0.0254 0.0086 0.0195 0.0038 0.0112 0.0102 0.0097 0.0071 0.0105 0.0012 0.0032 0.0029
Punctate Nuclear 0 0 0 0 0 0 0.0004 0 0.0007 0 0 0 0.0001 0 0.0002 0.0005 0 0
Vacuole 0.0031 0.0009 0.0004 0.0003 0.0005 0.0003 0.002 0.0003 0.0005 0.0001 0.0001 0.0003 0.0006 0.0022 0.0003 0.0017 0.0002 0.0002
Vacuole Periphery 0.0045 0.0072 0.0055 0.004 0.0022 0.0029 0.0114 0.0021 0.0011 0.0007 0.0005 0.0038 0.008 0.0087 0.0028 0.0125 0.0126 0.0027

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 53.3262 51.6801 60.168 80.9974 62.6781 53.7948 48.8752 54.7257 64.2744 55.059
Translational Efficiency 1.291 1.2675 1.5706 1.5024 1.6627 1.5227 1.536 1.6913 1.648 1.5076

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1237 2032 1121 1034 1551 1482 1096 1752 2788 3514 2217 2786

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 823.51 1137.33 1611.50 2010.07 922.53 1092.97 1513.83 2090.07 878.60 1118.62 1563.22 2060.38
Standard Deviation 149.89 228.71 333.93 554.90 163.55 242.15 295.49 577.97 165.13 235.49 319.27 570.83
Intensity Change Log 2 — 0.465793 0.968546 1.287388 — 0.244586 0.714535 1.179884 — 0.353151 0.839922 1.231587

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002111 0.010540 0.005433 0.009406 0.016201 0.011801 0.002770 0.004831 0.009949 0.011072 0.004116 0.006529
Bud Neck 0.002228 0.000933 0.002136 0.001811 0.001798 0.001578 0.001520 0.000958 0.001989 0.001205 0.001831 0.001274
Bud Site 0.002796 0.002471 0.001328 0.003036 0.001855 0.001751 0.001532 0.001337 0.002273 0.002167 0.001429 0.001968
Cell Periphery 0.000326 0.000155 0.000088 0.000356 0.000283 0.000145 0.000052 0.000283 0.000302 0.000151 0.000070 0.000310
Cytoplasm 0.000506 0.001098 0.000260 0.000375 0.000581 0.000585 0.000302 0.000341 0.000548 0.000881 0.000281 0.000353
Cytoplasmic Foci 0.011755 0.026221 0.029563 0.010849 0.014110 0.021588 0.013191 0.006274 0.013065 0.024267 0.021469 0.007972
Eisosomes 0.000062 0.000537 0.000640 0.000862 0.000593 0.000830 0.000234 0.000707 0.000357 0.000660 0.000439 0.000765
Endoplasmic Reticulum 0.000214 0.000179 0.000255 0.000611 0.000231 0.000169 0.000074 0.000119 0.000223 0.000175 0.000165 0.000302
Endosome 0.022818 0.013112 0.004306 0.003490 0.015714 0.008586 0.003778 0.001706 0.018866 0.011203 0.004045 0.002368
Golgi 0.021415 0.071007 0.045327 0.036165 0.038357 0.049853 0.021208 0.019706 0.030840 0.062086 0.033403 0.025815
Lipid Particles 0.005689 0.016991 0.008847 0.005501 0.017919 0.014359 0.002717 0.001663 0.012493 0.015881 0.005817 0.003087
Mitochondria 0.897029 0.822396 0.858566 0.889309 0.836532 0.841628 0.926352 0.941446 0.863374 0.830507 0.892077 0.922096
Mitotic Spindle 0.001044 0.001849 0.002342 0.004939 0.000626 0.001774 0.003960 0.000819 0.000811 0.001817 0.003142 0.002348
None 0.000273 0.000688 0.004232 0.003097 0.000543 0.000829 0.001036 0.001960 0.000423 0.000748 0.002652 0.002382
Nuclear Periphery 0.000072 0.000149 0.001222 0.000609 0.000155 0.000148 0.000587 0.000168 0.000119 0.000149 0.000908 0.000331
Nuclear Periphery Foci 0.000143 0.000162 0.000585 0.000224 0.000215 0.000202 0.000309 0.000092 0.000183 0.000179 0.000448 0.000141
Nucleolus 0.000169 0.000162 0.000651 0.000459 0.000176 0.000560 0.000258 0.000317 0.000173 0.000330 0.000456 0.000370
Nucleus 0.000134 0.000075 0.000083 0.000085 0.000083 0.000190 0.000069 0.000065 0.000106 0.000124 0.000076 0.000073
Peroxisomes 0.025481 0.027318 0.009926 0.005866 0.051596 0.037425 0.009995 0.005779 0.040009 0.031580 0.009960 0.005812
Vacuole 0.002122 0.001747 0.006376 0.006762 0.001241 0.003606 0.004129 0.004274 0.001632 0.002531 0.005265 0.005197
Vacuole Periphery 0.003615 0.002211 0.017835 0.016188 0.001190 0.002394 0.005927 0.007154 0.002266 0.002288 0.011948 0.010507

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -8.85 -3.47 -4.60 0.61 -2.20 2.09 6.99 5.74 5.06 -1.94 -0.91 5.00 2.65 4.31 -2.51
Bud Neck 1.55 0.09 0.46 -3.42 0.83 0.52 0.62 2.02 1.89 1.69 1.82 0.32 1.57 -0.38 2.16
Bud Site 0.37 1.94 -0.25 -0.59 -1.88 0.17 0.52 0.92 0.74 0.37 0.19 1.80 0.53 0.37 -1.14
Cell Periphery 3.13 5.18 -0.26 -1.64 -2.24 3.03 5.67 -0.02 -1.74 -3.00 4.19 7.60 -0.14 -2.34 -3.65
Cytoplasm -1.85 2.02 0.92 2.35 -1.62 -0.03 1.93 1.48 2.06 -0.38 -1.69 2.78 1.74 2.83 -1.12
Cytoplasmic Foci -8.19 -6.76 0.58 8.78 7.14 -4.55 0.52 5.92 9.80 4.19 -9.19 -5.29 5.05 13.84 8.67
Eisosomes -13.35 -10.47 -7.49 -2.89 -1.85 -2.63 6.06 -0.95 0.96 -4.39 -6.31 -1.88 -4.86 -1.22 -3.92
Endoplasmic Reticulum 0.98 -0.90 -1.66 -1.80 -1.48 1.62 4.46 3.00 2.19 -2.68 1.76 1.99 -0.86 -1.40 -1.50
Endosome 4.03 8.30 8.64 7.74 0.95 4.29 7.64 9.34 8.34 3.48 5.31 11.23 12.76 11.57 3.42
Golgi -13.05 -6.42 -3.84 7.43 1.98 -2.93 4.97 5.82 8.60 0.50 -11.05 -0.98 2.09 12.68 2.88
Lipid Particles -6.20 -2.27 0.13 6.37 2.45 1.36 7.66 8.23 7.15 2.06 -2.07 5.19 7.47 10.54 4.11
Mitochondria 8.50 4.08 0.85 -7.11 -3.05 -0.53 -10.23 -13.34 -12.90 -2.30 4.99 -4.36 -9.87 -15.75 -5.19
Mitotic Spindle -1.81 -2.74 -2.61 -2.01 -1.69 -1.99 -3.51 -0.85 1.63 3.29 -2.84 -4.40 -2.68 -0.84 1.05
None -7.85 -11.98 -15.00 -12.43 2.99 -3.95 -7.60 -14.55 -10.44 -8.94 -7.22 -12.83 -21.07 -16.69 1.39
Nuclear Periphery -3.64 -6.10 -6.48 -5.46 2.99 0.09 -2.67 -0.15 -0.65 2.94 -0.66 -6.26 -3.82 -5.00 4.69
Nuclear Periphery Foci -0.60 -4.23 -2.30 -1.77 3.40 0.20 -1.06 2.17 2.84 2.90 0.11 -3.79 1.18 1.49 4.73
Nucleolus 0.19 -2.30 -2.75 -3.21 0.88 -1.86 -1.14 -1.56 1.17 -0.75 -1.57 -2.55 -2.86 -0.41 0.76
Nucleus 1.41 1.38 1.28 -0.38 -0.15 -0.95 0.34 0.46 1.13 0.11 -0.34 1.09 1.18 1.01 0.14
Peroxisomes -0.52 4.99 6.52 9.28 2.12 3.06 10.60 12.40 10.13 2.22 2.93 11.61 13.89 13.89 3.10
Vacuole 0.94 -6.04 -3.85 -4.20 -0.35 -3.21 -4.84 -3.76 -0.64 -0.15 -2.39 -7.90 -5.26 -3.65 0.05
Vacuole Periphery 2.55 -8.67 -6.80 -7.69 0.68 -3.02 -7.27 -8.66 -6.09 -1.31 -0.08 -10.85 -10.02 -9.90 1.22
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit 2 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Qcr2

Qcr2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Qcr2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available