Standard name
Human Ortholog
Description Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; Mic19p is peripheral to the inner membrane and may connect Mic60p with the Mic10p-Mic12p-Mic27p subcomplex; both yeast and human Mic19p become oxidized, and oxidation may regulate MICOS
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.16 0.31 0.32 0.32 0.21 0.12 0.15 – 0.13 0.15 0.15 0.18 0.34 0.41 0.31 0.27 0.24 0.26 0.16 0.15 0.11 0.19 0.27 0.25
Bud 0 0.05 0 0.09 0.05 0.05 0 – 0 0.08 0 0 0 0.06 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.07 0 0.05 0 0 0 – 0 0 0 0 0.07 0 0 0.06 0.11 0 0 0 0 0 0 0
Cytoplasm 0.11 0.29 0.08 0.25 0.21 0.23 0.19 – 0.18 0.14 0.12 0.13 0.17 0.16 0.13 0.41 0.45 0.38 0 0.12 0 0 0 0
Endoplasmic Reticulum 0.33 0.33 0 0.19 0.2 0.17 0.12 – 0.2 0.14 0.2 0.19 0.36 0.2 0.23 0.07 0.06 0.06 0.19 0.1 0.08 0.24 0.19 0.14
Endosome 0.25 0.05 0.4 0.12 0.16 0.1 0.22 – 0.12 0.2 0.1 0.1 0.07 0.17 0.16 0 0 0.13 0.27 0.21 0.3 0.21 0.19 0.25
Golgi 0.16 0.11 0.2 0.14 0.12 0.07 0.16 – 0.05 0.1 0.09 0.14 0.23 0.19 0.36 0.18 0.1 0.18 0.12 0.08 0.15 0.12 0.15 0.17
Mitochondria 0 0 0 0.05 0 0.24 0.06 – 0.32 0.33 0.4 0.35 0 0 0 0 0.06 0.07 0.08 0.08 0.2 0.07 0.06 0.06
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.05 0.05 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.17 0.05 0.16 0.06 0.2 0.23 0.23 – 0.13 0.1 0.11 0.08 0 0.05 0 0.07 0.05 0.06 0 0.14 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 15 17 8 49 39 21 44 – 25 32 32 49 57 140 86 34 15 27 22 19 7 26 65 75
Bud 2 3 1 14 9 8 4 – 5 16 5 12 5 19 6 6 1 4 2 4 2 2 2 3
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 2 5 1 2 6 7
Bud Site 0 0 0 0 0 1 0 – 0 1 2 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 4 0 7 7 1 4 – 4 5 6 5 11 15 8 8 7 4 0 0 0 1 1 2
Cytoplasm 11 16 2 39 40 39 55 – 35 29 26 36 28 53 36 52 28 39 5 15 1 5 7 6
Endoplasmic Reticulum 32 18 1 30 38 29 35 – 40 29 44 52 60 69 64 9 4 6 27 12 5 32 44 40
Endosome 24 3 10 19 30 16 64 – 24 42 22 28 12 58 43 5 1 13 37 26 20 28 45 74
Golgi 15 6 5 22 23 11 46 – 10 20 20 37 38 63 99 23 6 19 17 9 10 16 36 50
Mitochondria 3 2 1 8 2 40 18 – 63 68 86 94 1 7 2 2 4 7 11 10 14 8 15 17
Nucleus 0 0 0 2 2 2 2 – 0 0 0 1 0 0 0 2 0 1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 1 1 – 2 0 0 0 0 0 1 0 0 0 2 0 0 1 1 1
Nucleolus 2 0 0 1 0 2 2 – 4 5 3 4 2 2 0 0 0 1 0 0 0 0 0 0
Peroxisomes 1 0 1 0 0 0 1 – 0 0 1 0 0 3 4 0 0 0 1 0 1 0 4 7
SpindlePole 1 0 0 7 9 1 13 – 1 7 3 9 2 10 4 2 0 4 1 1 0 0 2 2
Vac/Vac Membrane 16 3 4 10 37 38 66 – 25 21 23 22 4 17 7 9 3 6 5 17 0 4 3 5
Unique Cell Count 96 55 25 155 189 168 289 198 208 215 268 167 338 276 128 62 103 142 126 69 136 241 298
Labelled Cell Count 124 72 33 208 236 210 355 238 275 273 351 220 456 360 152 69 131 142 126 69 136 241 298


Cytoplasm, Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 12.0 11.9 10.2 10.5 11.1 7.9 9.9 – 8.5 8.7 8.5 8.9 13.3 11.0 13.3 13.6 14.9 13.8 10.9 11.3 11.3
Std Deviation (1e-4) 1.6 1.5 1.3 1.6 1.6 1.7 1.4 – 1.4 1.4 1.4 1.6 1.8 1.9 1.8 2.3 2.8 2.6 1.5 1.8 1.6
Intensity Change (Log2) – – – 0.04 0.13 -0.38 -0.05 – -0.26 -0.23 -0.27 -0.2 0.39 0.11 0.39 0.42 0.55 0.44 0.09 0.14 0.15


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 -1.3 0 0 – 0 0 0 0 0.2 0.9 -0.1 -0.6 -0.7 -0.6
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.9 0 1.7 0 – 0 0 0 0 0 0 0 3.1 3.3 2.9
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 3.2 0 2.2 0 0 0
Endosome 0 0 0 -2.0 – 0 -2.2 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0.3 0 1.6 0 0 0
Mitochondria 0 0 2.3 0 – 2.9 3.0 3.5 3.2 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0.7 0.8 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.2444 8.768 7.7032 7.4261 6.0137 7.9832 9.7785 11.6283 10.6003 10.0791 10.7371 10.5475 11.0495 13.3396 12.3013 12.7511 11.1304 12.1593
Actin 0.0331 0.0605 0.0608 0.0147 0.098 0.0329 0.0581 0.0576 0.0511 0.1193 0.0977 0.0368 0.0447 0.0602 0.0529 0.0614 0.0668 0.0453
Bud 0.0024 0.0061 0.0048 0.0012 0.002 0.0018 0.0019 0.0035 0.0046 0.0072 0.0072 0.0017 0.0016 0.0066 0.0029 0.0039 0.0057 0.0024
Bud Neck 0.0029 0.004 0.0143 0.0048 0.0094 0.0228 0.0043 0.003 0.0108 0.0118 0.012 0.0225 0.0032 0.0054 0.0156 0.0165 0.049 0.0622
Bud Periphery 0.0029 0.0062 0.005 0.0021 0.0026 0.003 0.0021 0.0022 0.0049 0.0104 0.0059 0.0024 0.0021 0.0059 0.0044 0.0073 0.0047 0.0032
Bud Site 0.0088 0.0547 0.0132 0.0023 0.0048 0.0025 0.011 0.039 0.0139 0.0071 0.0051 0.0017 0.0142 0.1066 0.0135 0.0029 0.0085 0.006
Cell Periphery 0.0024 0.0045 0.0027 0.0017 0.0026 0.0059 0.0049 0.0027 0.0023 0.0016 0.001 0.0017 0.005 0.0111 0.01 0.0049 0.0015 0.0031
Cytoplasm 0.1824 0.2196 0.1686 0.179 0.1873 0.181 0.1926 0.2167 0.2379 0.1281 0.2454 0.1542 0.2862 0.324 0.3274 0.2885 0.3006 0.2136
Cytoplasmic Foci 0.104 0.1066 0.0905 0.1042 0.1451 0.0992 0.0961 0.1166 0.0956 0.1028 0.2003 0.0949 0.0922 0.0852 0.1071 0.0739 0.118 0.0895
Eisosomes 0.0002 0.0005 0.0004 0 0.0004 0.0007 0.0003 0.0002 0.0002 0.0008 0 0.0003 0.0005 0.0002 0.0003 0.0001 0.0002 0.0004
Endoplasmic Reticulum 0.0817 0.0792 0.1052 0.0988 0.0343 0.0992 0.1005 0.0666 0.0577 0.1335 0.013 0.0733 0.1606 0.0514 0.1028 0.0806 0.0593 0.1325
Endosome 0.3077 0.2156 0.2465 0.2622 0.1836 0.2728 0.2329 0.2404 0.2544 0.2926 0.2583 0.2513 0.159 0.1575 0.1538 0.2969 0.1996 0.2189
Golgi 0.1354 0.1274 0.1605 0.1468 0.186 0.1588 0.118 0.1558 0.1366 0.1042 0.0912 0.2353 0.0781 0.0868 0.1112 0.0899 0.1281 0.1318
Lipid Particles 0.0482 0.0285 0.0383 0.1133 0.0447 0.0297 0.0604 0.0296 0.0347 0.0082 0.0153 0.0181 0.067 0.036 0.0365 0.0111 0.0159 0.0297
Mitochondria 0.0232 0.0267 0.0288 0.0109 0.0377 0.0535 0.0193 0.013 0.0413 0.0142 0.0075 0.0577 0.0166 0.0188 0.0128 0.0086 0.0132 0.0224
None 0.0016 0.0009 0.001 0.0005 0.0174 0.0008 0.0036 0.001 0.0012 0.0006 0.0007 0.0008 0.0088 0.0008 0.0013 0.0006 0.001 0.0006
Nuclear Periphery 0.0115 0.0038 0.0059 0.0092 0.0028 0.0049 0.0215 0.0089 0.0047 0.0055 0.0025 0.012 0.0198 0.0032 0.0037 0.0033 0.0051 0.0072
Nucleolus 0.0004 0.0014 0.0004 0.0001 0.0005 0.0002 0.001 0.0003 0.0009 0.0003 0.0002 0.0003 0.0004 0.0011 0.0019 0.0002 0.0001 0.0002
Nucleus 0.002 0.0088 0.0022 0.0015 0.0012 0.0014 0.0074 0.0014 0.0095 0.0012 0.0015 0.0036 0.0042 0.0024 0.002 0.0016 0.0015 0.0017
Peroxisomes 0.0104 0.0055 0.0099 0.0047 0.0194 0.0043 0.0134 0.0034 0.0071 0.011 0.0064 0.0041 0.0043 0.0029 0.0066 0.0012 0.0095 0.0045
Punctate Nuclear 0.0023 0.0013 0.0013 0.0008 0.0079 0.0008 0.0049 0.0009 0.0012 0.0013 0.0013 0.0009 0.01 0.001 0.0106 0.001 0.0016 0.0012
Vacuole 0.0306 0.0345 0.0338 0.0344 0.0095 0.0181 0.0393 0.033 0.0249 0.0267 0.023 0.0202 0.0181 0.0302 0.0203 0.031 0.0087 0.0205
Vacuole Periphery 0.006 0.0038 0.0058 0.0067 0.0029 0.0057 0.0065 0.0042 0.0046 0.0117 0.0043 0.0063 0.0034 0.0027 0.0024 0.0144 0.0018 0.0031

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.9808 11.5366 8.5606 13.43 13.9436 8.5988 18.469 11.1532 18.1505 16.1236
Translational Efficiency 3.1942 2.056 2.8301 1.913 2.0821 6.0918 2.0553 3.3803 2.8484 3.4276

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2154 227 1792 61 1480 1829 1718 963 3634 2056 3510 1024

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1081.82 1301.10 1438.71 1427.67 1062.61 1194.92 1406.25 1335.17 1074.00 1206.64 1422.82 1340.68
Standard Deviation 140.00 172.48 217.06 189.17 146.33 167.60 204.95 206.49 142.93 171.41 211.84 206.66
Intensity Change Log 2 — 0.266271 0.411315 0.400202 — 0.169302 0.404241 0.329411 — 0.219035 0.407814 0.365558

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.023310 0.063119 0.025142 0.026129 0.024603 0.037828 0.037801 0.017921 0.023837 0.040621 0.031338 0.018410
Bud Neck 0.006964 0.008856 0.004147 0.011710 0.003870 0.005512 0.008264 0.006942 0.005704 0.005881 0.006162 0.007226
Bud Site 0.080802 0.155388* 0.141690* 0.232930* 0.053614 0.085761 0.227054* 0.252868* 0.069729 0.093449 0.183472* 0.251681*
Cell Periphery 0.001584 0.005026 0.002719 0.001472 0.001237 0.001784 0.002944 0.002241 0.001443 0.002142 0.002829 0.002196
Cytoplasm 0.026188 0.024081 0.099395 0.073171 0.021288 0.027432 0.106682* 0.182496* 0.024192 0.027062 0.102962* 0.175984*
Cytoplasmic Foci 0.177865 0.147434 0.136852 0.130904 0.220516* 0.171857 0.142286 0.149526 0.195235* 0.169160 0.139512 0.148417
Eisosomes 0.000595 0.000507 0.000154 0.000110 0.000337 0.000716 0.000174 0.000096 0.000490 0.000693 0.000164 0.000097
Endoplasmic Reticulum 0.025145 0.034373 0.021530 0.002988 0.024027 0.016989 0.021480 0.003655 0.024690 0.018909 0.021506 0.003616
Endosome 0.250620* 0.199300 0.087067 0.172510 0.229927* 0.222477* 0.110353 0.095782 0.242192* 0.219918* 0.098465 0.100353
Golgi 0.261318* 0.270560* 0.293872* 0.062970 0.303895* 0.296848* 0.176685* 0.114124* 0.278658* 0.293946* 0.236514* 0.111077*
Lipid Particles 0.014915 0.016748 0.021600 0.009821 0.017862 0.013749 0.025140 0.007952 0.016115 0.014080 0.023333 0.008063
Mitochondria 0.052806 0.015492 0.012135 0.000189 0.026169 0.056365 0.006333 0.008676 0.041958 0.051852 0.009295 0.008170
Mitotic Spindle 0.002189 0.008076 0.020758 0.032233 0.004652 0.004065 0.010166 0.016335 0.003192 0.004508 0.015574 0.017282
None 0.000083 0.000058 0.000258 0.000028 0.000065 0.000568 0.000099 0.000089 0.000076 0.000511 0.000180 0.000085
Nuclear Periphery 0.000136 0.000053 0.000189 0.000478 0.000159 0.000059 0.000119 0.000066 0.000145 0.000058 0.000155 0.000091
Nuclear Periphery Foci 0.001285 0.001202 0.005588 0.002779 0.003055 0.000812 0.003898 0.000931 0.002006 0.000855 0.004761 0.001041
Nucleolus 0.000184 0.000017 0.000050 0.000448 0.000078 0.000087 0.000051 0.000118 0.000141 0.000080 0.000051 0.000138
Nucleus 0.000537 0.000165 0.000549 0.000979 0.000376 0.000252 0.000640 0.000566 0.000471 0.000242 0.000594 0.000591
Peroxisomes 0.006713 0.007481 0.002449 0.014731 0.006522 0.007724 0.006522 0.009971 0.006635 0.007697 0.004443 0.010254
Vacuole 0.038877 0.030902 0.088381 0.204201* 0.034786 0.028047 0.093709 0.105394 0.037211 0.028362 0.090989 0.111280
Vacuole Periphery 0.027883 0.011163 0.035474 0.019220 0.022964 0.021067 0.019597 0.024250 0.025880 0.019974 0.027703 0.023950

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.46 -0.68 -0.01 2.99 0.17 -3.83 -3.83 2.28 6.15 6.29 -5.79 -3.45 2.38 7.09 5.26
Bud Neck -1.29 4.85 -2.51 -1.26 -3.97 -3.27 -9.19 -5.48 -2.64 1.94 -0.36 -1.73 -3.02 -2.57 -2.02
Bud Site -5.22 -11.52 -4.38 -1.85 -2.41 -6.98 -27.88* -23.84 -19.57 -2.49 -5.73 -27.24 -22.96 -18.86 -7.82
Cell Periphery -2.11 -4.82 0.54 2.18 2.67 -2.79 -4.69 -3.22 -1.31 1.67 -2.90 -6.45 -2.60 0.03 2.09
Cytoplasm 0.54 -18.30 -3.06 -3.12 1.14 -2.72 -20.44 -22.95 -22.12 -9.48 -1.56 -27.25 -22.89 -22.25 -10.12
Cytoplasmic Foci 3.49 10.47 3.28 1.24 0.58 9.52 15.97 11.72 4.14 -1.41 6.73 18.02 9.38 4.10 -1.90
Eisosomes 0.93 7.15 7.39 5.24 1.82 -6.54 7.54 11.35 11.29 6.25 -3.29 8.68 10.36 12.03 6.78
Endoplasmic Reticulum -1.18 1.44 11.77 4.08 10.29 2.68 0.94 9.30 8.20 9.55 2.78 1.73 14.88 9.07 13.77
Endosome 4.03 34.46* 4.12 1.62 -3.29 1.17 22.46 23.18 23.52 3.45 4.36 40.19* 30.21 22.90 -0.20
Golgi -0.55 -3.39 15.24 10.72 16.63 0.87 17.50 24.51 24.30 8.73 -2.38 8.78 27.27 25.69 19.35*
Lipid Particles -0.53 -4.22 1.98 1.68 4.66 2.03 -3.41 5.28 3.30 8.73 1.30 -5.54 5.98 3.67 10.94
Mitochondria 8.27 14.78 21.02 4.08 9.66 -8.13 8.85 7.37 14.72 -1.64 -3.04 17.55 16.71 14.83 0.85
Mitotic Spindle -1.43 -10.77 -1.90 -1.51 -0.77 0.58 -5.41 -5.04 -5.31 -2.93 -1.58 -12.34 -6.01 -5.38 -1.21
None 2.30 -12.70 3.22 1.47 12.36 -1.13 -4.38 -1.20 1.07 0.45 -1.10 -12.80 -0.60 1.07 4.67
Nuclear Periphery 2.95 -1.83 -1.25 -1.52 -1.07 3.32 1.02 2.86 -1.07 2.72 4.16 -0.64 1.62 -1.87 2.53
Nuclear Periphery Foci 0.28 -8.25 -1.83 -1.90 1.69 2.90 -1.38 2.69 -0.91 7.39 3.10 -6.55 2.33 -1.45 10.86
Nucleolus 1.24 0.97 -0.74 -1.26 -1.16 -0.14 0.58 -1.06 -1.00 -1.75 0.67 1.08 -0.39 -1.39 -2.04
Nucleus 1.62 -0.34 -1.33 -1.91 -1.29 0.77 -1.73 -1.59 -3.94 -0.16 1.50 -1.17 -1.55 -4.41 -0.95
Peroxisomes -0.61 8.45 -2.36 -1.99 -3.80 -1.44 0.17 -3.40 -2.55 -4.17 -1.78 4.93 -4.32 -2.96 -7.74
Vacuole 1.43 -13.49 -6.43 -6.61 -4.70 2.59 -14.76 -12.94 -14.58 -1.62 4.31 -19.89 -14.19 -15.70 -3.57
Vacuole Periphery 7.91 -3.94 1.57 -0.84 2.56 1.20 2.33 -0.31 -1.31 -2.23 4.87 -1.16 1.46 -1.74 2.20
Standard name
Human Ortholog
Description Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; Mic19p is peripheral to the inner membrane and may connect Mic60p with the Mic10p-Mic12p-Mic27p subcomplex; both yeast and human Mic19p become oxidized, and oxidation may regulate MICOS
Localization
Cell Percentages mitochondrion (11%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mic19

Mic19


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mic19-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available